Haywood L J
University of Southern California School of Medicine, Los Angeles.
Am J Hypertens. 1989 Nov;2(11 Pt 1):865-8. doi: 10.1093/ajh/2.11.865.
Previously reported data document that efficacy of beta-adrenergic antagonists in lowering mortality rates after acute myocardial infarction. Similarly, the higher observed mortality rates among blacks in the Beta-Blocker Heart Attack Trial (BHAT) have been addressed. In this report, we further emphasize the apparent role of prior high blood pressure in the high risk profile of black patients radomized in the BHAT and the similarity in response to therapy to other high risk patients in this study.
先前报道的数据证明了β-肾上腺素能拮抗剂在降低急性心肌梗死后死亡率方面的疗效。同样,β受体阻滞剂心脏病发作试验(BHAT)中黑人中观察到的较高死亡率也已得到探讨。在本报告中,我们进一步强调了既往高血压在BHAT研究中随机分组的黑人患者高风险特征中的明显作用,以及该研究中这些黑人患者与其他高风险患者在治疗反应上的相似性。