Subdirectorate for Health Promotion and Prevention, Madrid Regional Health Authority, C/ San Martín de Porres, 6, 28035 Madrid, Spain.
Subdirectorate for Health Promotion and Prevention, Madrid Regional Health Authority, C/ San Martín de Porres, 6, 28035 Madrid, Spain.
J Infect. 2015 Jul;71(1):85-92. doi: 10.1016/j.jinf.2015.01.015. Epub 2015 Mar 3.
This study aimed to estimate herpes zoster (HZ) related hospitalization rates in the Autonomous Community of Madrid (Spain), considering both total and complicated cases, and to analyze their temporal trends by sex and age.
Population based cross-sectional study of all hospital admissions with an HZ diagnosis in any position from 2003 to 2013. Annual crude, age-adjusted and age-specific hospitalization rates were calculated by sex and year. Joinpoint Regression models were used to analyze time trends.
The incidence of hospitalizations with HZ increased significantly during the study period from 10.81 to 16.97 per 100,000 person-year, with an average annual rise of 2.80%. The rate of hospitalization of complicated HZ increased from 4.67 to 8.99 per 100,000 person-year. No 'breakthrough points' of the time trends were detected. The proportion of complicated HZ was similar in both sexes, and increased from 43.2% to 53.0%. By age and sex significant increases affecting women from age 85 and men from age 75 and in the group of 45-64 years were observed.
Hospitalizations related to HZ are increasing, with a significant rise of complicated cases. Long term and more detailed studies are required to monitor HZ.
本研究旨在估算西班牙马德里自治区（Madrid，Spain）的带状疱疹（herpes zoster，HZ）相关住院率，包括总病例和复杂病例，并按性别和年龄分析其时间趋势。
本研究为 2003 年至 2013 年期间所有位置的 HZ 诊断的住院患者进行的基于人群的横断面研究。按性别和年份计算了每年的粗住院率、年龄调整住院率和年龄特异性住院率。采用 Joinpoint 回归模型分析时间趋势。
在研究期间，HZ 住院的发病率显著增加，从每 10 万人年 10.81 例增至 16.97 例，年均增长率为 2.80%。复杂 HZ 的住院率从每 10 万人年 4.67 例增至 8.99 例。未发现时间趋势的“突破点”。两性的复杂 HZ 住院率相似，从 43.2%增至 53.0%。按年龄和性别分层，85 岁以上女性、75 岁以上男性以及 45-64 岁人群的增长率显著增加。
HZ 相关住院率呈上升趋势，复杂病例显著增加。需要进行长期和更详细的研究来监测 HZ。
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