L-酪氨酸诱导黑色素生成相关蛋白的合成。
L-tyrosine induces synthesis of melanogenesis related proteins.
作者信息
Slominski A
机构信息
H. W. Toolan Institute for Medical Research, Bennington, VT 05201.
出版信息
Life Sci. 1989;45(19):1799-803. doi: 10.1016/0024-3205(89)90520-1.
PMID:2574401
Abstract
In cultured amelanotic hamster melanoma cells L-tyrosine induces melanogenesis. This induction involves an increase in intracellular concentration of proteins precipitated by polyclonal anti-tyrosinase antibodies, and stimulation of the Vmax of tyrosinase activity. Therefore it is suggested that in hamster melanoma cells L-tyrosine induces synthesis of tyrosinase and melanogenesis related proteins.
摘要
在培养的无黑色素仓鼠黑色素瘤细胞中，L-酪氨酸可诱导黑色素生成。这种诱导作用涉及多克隆抗酪氨酸酶抗体沉淀的蛋白质细胞内浓度的增加，以及酪氨酸酶活性Vmax的刺激。因此，有人认为在仓鼠黑色素瘤细胞中，L-酪氨酸可诱导酪氨酸酶和黑色素生成相关蛋白的合成。
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