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电风暴的最佳抗心律失常药物治疗

Optimal antiarrhythmic drug therapy for electrical storm.

作者信息

Sorajja Dan, Munger Thomas M, Shen Win-Kuang

机构信息

Division of Cardiovascular Diseases, Mayo Clinic Arizona, Phoenix, AZ 85054, USA.

出版信息

J Biomed Res. 2015 Jan;29(1):20-34. doi: 10.7555/JBR.29.20140147. Epub 2015 Jan 15.

DOI:10.7555/JBR.29.20140147
PMID:25745472
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4342432/
Abstract

Electrical storm, defined as 3 or more separate episodes of ventricular tachycardia or ventricular fibrillation within 24 hours, carries significant morbidity and mortality. These unstable ventricular arrhythmias have been described with a variety of conditions including ischemic heart disease, structural heart disease, and genetic conditions. While implantable cardioverter defibrillator implantation and ablation may be indicated and required, antiarrhythmic medication remains an important adjunctive therapy for these persons.

摘要

电风暴定义为24小时内发生3次或更多次独立的室性心动过速或室性颤动发作，具有显著的发病率和死亡率。这些不稳定的室性心律失常与多种疾病有关，包括缺血性心脏病、结构性心脏病和遗传性疾病。虽然可能需要植入式心脏复律除颤器植入和消融治疗，但抗心律失常药物仍然是这些患者重要的辅助治疗方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6fb2/4342432/c8fb7cbe6b94/jbr-29-01-020-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6fb2/4342432/6e7137f2d0cb/jbr-29-01-020-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6fb2/4342432/438695db6a3d/jbr-29-01-020-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6fb2/4342432/c8fb7cbe6b94/jbr-29-01-020-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6fb2/4342432/6e7137f2d0cb/jbr-29-01-020-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6fb2/4342432/438695db6a3d/jbr-29-01-020-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6fb2/4342432/c8fb7cbe6b94/jbr-29-01-020-g003.jpg

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