Schmidt Marcello F S, Gernand Jill, Kakarala Radhika
Department of Internal Medicine, McLaren Flint, Flint, MI.
Department of Mathematics, Kettering University, Flint, MI.
J Crit Care. 2015 Jun;30(3):486-90. doi: 10.1016/j.jcrc.2015.02.007. Epub 2015 Feb 24.
To determine the relationship between the pulse oximetric saturation to fraction of inspired oxygen (SF) ratio and the arterial partial pressure of oxygen to the fraction of inspired oxygen (PF) ratio, and to assess the usefulness of the SF ratio in an automated acute respiratory distress syndrome (ARDS) screening tool.
This was a retrospective cohort study using the Multiparameter Intelligent Monitoring in Intensive Care II database. The relationship was derived and validated in all patients ventilated for at least 24 hours.
The total data set included 7544 paired measurements from 3767 intensive care unit admissions. The correlation between SF ratio and PF ratio in the whole data set was good (Spearman ρ = 0.72, P < .001). An automated ARDS diagnostic tool using the derived SF cutoff had excellent agreement with the same tool using the PF ratio of 300 (κ = 0.87).
The SF ratio may be an adequate substitute for the PF ratio in an automated ARDS screening tool.
确定脉搏血氧饱和度与吸入氧分数比（SF）和动脉血氧分压与吸入氧分数比（PF）之间的关系，并评估SF比值在自动急性呼吸窘迫综合征（ARDS）筛查工具中的实用性。
这是一项使用重症监护II数据库中的多参数智能监测的回顾性队列研究。在所有通气至少24小时的患者中得出并验证了这种关系。
数据集包括来自3767例重症监护病房入院患者的7544对测量值。整个数据集中SF比值与PF比值之间的相关性良好（Spearman ρ = 0.72，P <.001）。使用推导的SF临界值的自动ARDS诊断工具与使用PF比值300的相同工具具有极好的一致性（κ = 0.87）。
在自动ARDS筛查工具中，SF比值可能是PF比值的适当替代指标。
