Department of Epidemiology, Pasteur Institute of Iran, Tehran, Iran; National Reference Laboratory for Plague, Tularemia and Q Fever, Research Centre for Emerging and Reemerging Infectious Diseases, Pasteur Institute of Iran, Akanlu, Kabudar-Ahang, Hamadan, Iran.
Division of Cardiology, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
J Infect Public Health. 2015 Sep-Oct;8(5):498-501. doi: 10.1016/j.jiph.2014.12.004. Epub 2015 Mar 5.
In this report, we describe the first chronic case of Q fever endocarditis in a 72-year-old woman in Iran. The patient developed radiation-associated heart disease status post (s/p) coronary artery bypass surgery, mitral and aortic valve replacements, and tricuspid valve repair. Endocarditis was also suspected due to a history of heart valve surgery. Blood cultures were negative, but a diagnosis of Q fever endocarditis was confirmed based on serologic titers (IgG phase I 1:32,768). The patient was treated with doxycycline and hydroxychloroquine.
在本报告中,我们描述了伊朗一名 72 岁女性慢性 Q 热心内膜炎的首例病例。该患者患有放射性心脏病,曾接受过冠状动脉旁路手术、二尖瓣和主动脉瓣置换术以及三尖瓣修复术。由于心脏瓣膜手术史,也怀疑有心内膜炎。血培养为阴性,但基于血清学滴度(IgG 一期 1:32,768)确诊为 Q 热心内膜炎。该患者接受了多西环素和羟氯喹治疗。