Tikhonova T V, Popov V O
Bach Institute of Biochemistry, Russian Academy of Sciences, Moscow, 119071, Russia.
Biochemistry (Mosc). 2014 Dec;79(13):1584-601. doi: 10.1134/S0006297914130094.
Bacteria utilizing insoluble mineral forms of metal oxides as electron acceptors in respiratory processes are widespread in the nature. The electron transfer from a pool of reduced quinones in the cytoplasmic membrane across the periplasm to the bacterial outer membrane and then to an extracellular acceptor is a key step in bacterial dissimilatory metal reduction. Multiheme cytochromes c play a crucial role in the extracellular electron transfer. The bacterium Shewanella oneidensis MR-1 was used as a model organism to study the mechanism of extracellular electron transport. In this review, we discuss recent data on the composition, structures, and functions of multiheme cytochromes c and their functional complexes responsible for extracellular electron transport in Shewanella oneidensis.
在呼吸过程中利用不溶性金属氧化物矿物形式作为电子受体的细菌在自然界中广泛存在。电子从细胞质膜中还原醌池穿过周质转移到细菌外膜，然后再到细胞外受体，这是细菌异化金属还原的关键步骤。多血红素细胞色素c在细胞外电子转移中起关键作用。以嗜铁栖热袍菌MR-1为模式生物来研究细胞外电子传递机制。在这篇综述中，我们讨论了关于多血红素细胞色素c及其负责嗜铁栖热袍菌细胞外电子传递的功能复合物的组成、结构和功能的最新数据。
