Bingol Ugur Anil, Cinar Can, Cetinkale Oguz
Department of Plastic, Reconstructive and Aesthetic Surgery, Yeditepe Medical School, Yeditepe University, Istanbul, Turkey; and Department of Plastic, Reconstructive and Aesthetic Surgery, Cerrahpasa Medical School, Istanbul University, Istanbul, Turkey.
Plast Reconstr Surg Glob Open. 2015 Mar 6;3(2):e305. doi: 10.1097/GOX.0000000000000275. eCollection 2015 Feb.
Papillary thyroid carcinoma (PTC) is the most common and well-differentiated cancer of the thyroid. Unlike most cancers, spread to local lymph node does not worsen the survival rate of PTC, and complete resection of the metastases seems to be important and may have favorable effects on the prognosis. A 33-year-old woman was referred to our clinic with a mass involving the right angulus mandible. Incisional biopsy of the mass diagnosed follicular variant of papillary thyroid carcinoma. Right hemimandibulectomy was performed and reconstructed with costochondral rib graft. The patient survived for 5 years after the hemimandibulectomy. Metastases to the oral cavity indicate a grave prognosis, but PTC has relatively indolent biological behavior; long-term survival is usually possible even in patients with metastatic disease.
甲状腺乳头状癌(PTC)是甲状腺最常见且分化良好的癌症。与大多数癌症不同,扩散至局部淋巴结并不会降低PTC的生存率,而彻底切除转移灶似乎很重要,且可能对预后产生有利影响。一名33岁女性因右下颌角肿物被转诊至我院。肿物的切开活检诊断为甲状腺乳头状癌滤泡变体。实施了右半侧下颌骨切除术,并用肋软骨移植进行重建。该患者在半侧下颌骨切除术后存活了5年。口腔转移提示预后不佳,但PTC具有相对惰性的生物学行为;即使是患有转移性疾病的患者通常也有可能长期存活。