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重度脑损伤女性的妊娠延续情况。

Continuation of pregnancy in a woman with critical brain injury.

作者信息

Wawrzyniak Joanna

机构信息

Department of Anaesthesiology and Intensive Therapy, District Specialist Hospital in Słupsk, Poland.

出版信息

Anaesthesiol Intensive Ther. 2015;47(1):40-4. doi: 10.5603/AIT.2015.0005.

DOI:10.5603/AIT.2015.0005
PMID:25751292
Abstract

BACKGROUND

Critical brain injury can lead to brain death, which is medically and legally considered the death of an individual. Further therapy is discontinued, unless organ donation is possible or brain death occurs in a pregnant woman.

CASE REPORT

A 30-year old woman at 22 weeks gestation developed a subarachnoid haemorrhage from a ruptured cerebral artery aneurysm. The patient was admitted to the Intensive Care Unit in critical condition. On treatment day 3, the symptoms of brain death occurred. Due to possible complications, the apnoea test and instrumental examinations were not performed. Therapy maintaining vital functions was carried out in order to sustain the pregnancy. The patient was ventilated, received cardiac-supportive drugs, hormone replacement therapy, enteral and parenteral feedings and systemic infections were treated as well. At the beginning of the 27th week of gestation, massive bleeding from the airways developed. A Caesarean section was performed, and a female neonate was born, birth weight 680 g, the Apgar scores 4, 6 and 6 at 1st, 5th and 10th minute, respectively. After 3.5 months, the baby was discharged from the Neonatal Intensive Care Unit. Her development at the age of 8 months is normal.

CONCLUSIONS

The case described and similar cases reported in the literature demonstrate that the maternal brain death is an interdisciplinary medical challenge. Thanks to intensive care techniques, maternal somatic functions can be maintained, and a healthy child can be delivered.

摘要

背景

严重脑损伤可导致脑死亡,在医学和法律上脑死亡被视为个体死亡。除非有可能进行器官捐献或孕妇发生脑死亡,否则会停止进一步治疗。

病例报告

一名妊娠22周的30岁女性因脑动脉动脉瘤破裂发生蛛网膜下腔出血。患者病情危急,被收入重症监护病房。在治疗第3天,出现脑死亡症状。由于可能出现并发症,未进行呼吸暂停试验和仪器检查。为维持妊娠,进行了维持生命功能的治疗。患者接受了通气、心脏支持药物治疗、激素替代治疗、肠内和肠外营养支持,同时也对全身感染进行了治疗。在妊娠第27周初,患者气道大量出血。随后进行了剖宫产,一名女婴出生,出生体重680克,1分钟、5分钟和10分钟时的阿氏评分分别为4分、6分和6分。3.5个月后,婴儿从新生儿重症监护病房出院。其8个月时的发育正常。

结论

本文所述病例及文献报道的类似病例表明,母体脑死亡是一个跨学科的医学挑战。得益于重症监护技术,母体的躯体功能得以维持,且能够分娩出健康的婴儿。

相似文献

1
Continuation of pregnancy in a woman with critical brain injury.重度脑损伤女性的妊娠延续情况。
Anaesthesiol Intensive Ther. 2015;47(1):40-4. doi: 10.5603/AIT.2015.0005.
2
Pregnancy and subarachnoid hemorrhage: a case report.妊娠与蛛网膜下腔出血:一例病例报告
J Matern Fetal Neonatal Med. 2004 Oct;16(4):245-6. doi: 10.1080/14767050400014469.
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[A Case of Cesarean Section Preceded by Coil Embolization for Subarachnoid Hemorrhage under General Anesthesia].[全身麻醉下蛛网膜下腔出血行弹簧圈栓塞后剖宫产1例]
Masui. 2015 Sep;64(9):989-91.
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Subarachnoid hemorrhage due to cerebral aneurysmal rupture during pregnancy.
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A brain dead woman, giving birth in the 23rd week of pregnancy, used as an organ donor: a case report.一名脑死亡女性在怀孕第23周分娩,并被用作器官捐献者:一例病例报告。
Ann Transplant. 2012 Jan-Mar;17(1):113-6. doi: 10.12659/aot.882643.
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Anesthetic management of combined caesarean section and clipping of ruptured cerebral aneurysm.剖宫产联合破裂脑动脉瘤夹闭术的麻醉管理
J Pak Med Assoc. 2004 Jun;54(6):330-2.
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Subarachnoid hemorrhage secondary to ruptured cerebral aneurysm in pregnancy.妊娠期间因脑动脉瘤破裂继发蛛网膜下腔出血。
Obstet Gynecol. 1979 Jan;53(1):64-70.
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