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同卵 HLA 母女的额部纤维性秃发和扁平苔藓样毛发扁平苔藓

Frontal fibrosing alopecia and lichen planopilaris in HLA-identical mother and daughter.

作者信息

Rivas María Mercedes Otero, Antolín Sara Calleja, Sambucety Pedro Sánchez, González Elia Samaniego, Ruíz de Morales José María García, Prieto Manuel Ángel Rodríguez

机构信息

Department of Dermatology, Complejo Asistencial Universitario de León, Spain.

出版信息

Indian J Dermatol Venereol Leprol. 2015 Mar-Apr;81(2):162-5. doi: 10.4103/0378-6323.152284.

Abstract

Frontal fibrosing alopecia (FFA) is a lymphocyte-mediated scarring alopecia thought to be a variant of lichen planopilaris (LPP). We present a 67-year-old woman with frontal fibrosing alopecia whose daughter was diagnosed to have lichen planopilaris. Both patients had identical human leukocyte antigen (HLA) D types, supporting a phenotypical relationship between the two clinical entities. Interestingly, our patient also had of autoimmune chronic atrophic gastritis, a previously unreported association.

摘要

额部纤维性秃发(FFA)是一种淋巴细胞介导的瘢痕性秃发,被认为是扁平苔藓性毛发扁平苔藓(LPP)的一种变体。我们报告一名67岁患有额部纤维性秃发的女性,其女儿被诊断为扁平苔藓性毛发扁平苔藓。两名患者具有相同的人类白细胞抗原(HLA)D型,支持这两种临床实体之间的表型关系。有趣的是,我们的患者还患有自身免疫性慢性萎缩性胃炎,这是一种先前未报道的关联。

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