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对于法国年轻孕妇,沙眼衣原体、淋病奈瑟菌和生殖支原体的筛查是否应纳入常规孕期保健?

Screening for Chlamydia trachomatis, Neisseria gonorrhoeae, and Mycoplasma genitalium should it be integrated into routine pregnancy care in French young pregnant women?

作者信息

Peuchant O, Le Roy C, Desveaux C, Paris A, Asselineau J, Maldonado C, Chêne G, Horovitz J, Dallay D, de Barbeyrac B, Bébéar C

机构信息

Univ. Bordeaux, USC EA 3671 Mycoplasmal and Chlamydial Infections in Humans, 33076 Bordeaux, France; INRA, USC EA 3671 Mycoplasmal and Chlamydial Infections in Humans, 33076 Bordeaux, France; Centre Hospitalier Universitaire de Bordeaux, Laboratoire de Bactériologie, 33076 Bordeaux, France.

Univ. Bordeaux, USC EA 3671 Mycoplasmal and Chlamydial Infections in Humans, 33076 Bordeaux, France; INRA, USC EA 3671 Mycoplasmal and Chlamydial Infections in Humans, 33076 Bordeaux, France.

出版信息

Diagn Microbiol Infect Dis. 2015 May;82(1):14-9. doi: 10.1016/j.diagmicrobio.2015.01.014. Epub 2015 Feb 3.

DOI:10.1016/j.diagmicrobio.2015.01.014
PMID:25753079
Abstract

Chlamydia trachomatis, Neisseria gonorrhoeae, and Mycoplasma genitalium screening during pregnancy is not performed routinely in France. We conducted the first prospective study in 1004 women attending for routine antenatal care to determine the prevalence and risk factors for these bacterial infections. The overall prevalence of C. trachomatis, N. gonorrhoeae, and M. genitalium infections was 2.5%, 0%, and 0.8%, respectively. In patients aged 18-24 years, the prevalence increased to 7.9% for C. trachomatis and to 2.4% for M. genitalium. C. trachomatis infection was associated with age ≤24 years or being single or having more than 5 sexual partners in a lifetime. M. genitalium infection was more frequent in patients aged ≤24 years or who had a history of abortion or their first sexual intercourse after 20 years of age. The high prevalence of C. trachomatis in pregnant women aged ≤24 years, mostly asymptomatic, suggests that systematic screening could be beneficial.

摘要

在法国,孕期通常不进行沙眼衣原体、淋病奈瑟菌和生殖支原体的筛查。我们对1004名接受常规产前检查的女性进行了首次前瞻性研究,以确定这些细菌感染的患病率和危险因素。沙眼衣原体、淋病奈瑟菌和生殖支原体感染的总体患病率分别为2.5%、0%和0.8%。在18 - 24岁的患者中,沙眼衣原体患病率增至7.9%,生殖支原体患病率增至2.4%。沙眼衣原体感染与年龄≤24岁、单身或一生中有超过5个性伴侣有关。生殖支原体感染在年龄≤24岁、有流产史或20岁后首次发生性行为的患者中更为常见。≤24岁孕妇中沙眼衣原体的高患病率(大多无症状)表明进行系统性筛查可能有益。

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