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[莫斯科居民中与加利福尼亚脑炎复合体病毒相关疾病病例的临床实验室特征]

[The clinico-laboratory characteristics of cases of diseases connected with viruses of the California encephalitis complex in the inhabitants of Moscow].

作者信息

Kolobukhina L V, L'vov D K, Butenko A M, Kuznetsov A A, Galkina I V

出版信息

Zh Mikrobiol Epidemiol Immunobiol. 1989 Oct(10):68-73.

PMID:2575313
Abstract

To study the role of viruses of the California encephalitis virus complex (the family Bunyaviridae) in infectious pathology, 187 fever patients admitted to the Clinical Infectious Hospital in May-September 1986 were examined. In 10 of these patients the neutralization test revealed the presence of diagnostically significant changes in neutralizing antibodies (neutralization indices), which was indicative of the role played by Tahyna virus or other related viruses belonging to the California encephalitis virus complex in the etiology of the diseases. The analysis of the clinical picture showed that in all patients the disease took an acute course in its initial stage, starting with shivering and characterized by high fever, headache, pronounced toxicosis, the possibility of the formation of intracerebral hypertension and pneumonia.

摘要

为研究加利福尼亚脑炎病毒复合体(布尼亚病毒科)病毒在感染性病理学中的作用,对1986年5月至9月入住临床传染病医院的187例发热患者进行了检查。在其中10例患者中,中和试验显示中和抗体(中和指数)出现了具有诊断意义的变化,这表明塔希纳病毒或属于加利福尼亚脑炎病毒复合体的其他相关病毒在这些疾病的病因中发挥了作用。对临床症状的分析表明,所有患者在疾病初期均呈急性病程,始于寒战,其特征为高热、头痛、明显的中毒症状、可能形成颅内高压和肺炎。

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