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使用柔性带/环治疗功能性三尖瓣反流的三尖瓣环成形术的远期结果

Late outcome of tricuspid annuloplasty using a flexible band/ring for functional tricuspid regurgitation.

作者信息

Fukunaga Naoto, Okada Yukikatsu, Konishi Yasunobu, Murashita Takashi, Koyama Tadaaki

机构信息

Department of Cardiovascular Surgery, Kobe City Medical Center General Hospital.

出版信息

Circ J. 2015;79(6):1299-306. doi: 10.1253/circj.CJ-14-1282. Epub 2015 Mar 3.

Abstract

BACKGROUND

We assessed late outcome after tricuspid annuloplasty (TAP) using a flexible band or ring for functional tricuspid regurgitation (FTR).

METHODS AND RESULTS

We reviewed 220 consecutive patients (mean age, 65.4±11.4 years) who underwent TAP for FTR during mitral valve surgery between January 2000 and December 2010. Indications for TAP included the following: (1) TR grade greater than mild; (2) history of right heart failure; (3) atrial fibrillation; and (4) systolic pulmonary artery pressure (SPAP) ≥50 mmHg. The mean follow-up period was 4.4±2.6 years. Overall hospital mortality was 5.5% (12/220). The 5- and 10-year survival rates were 90.2±2.1% and 82.4±5.6%, respectively. Freedom from recurrent TR at 8 years was 78.0±6.6%. Twenty patients had a greater than mild TR grade at final follow-up. Elevated SPAP was a predictor of recurrent TR (hazard ratio, 1.091; P=0.0003), which was associated with advanced age, atrial fibrillation, rheumatic etiology and preoperative TR grade. There was a significant difference in freedom from valve-related events between residual TR greater than mild and less than moderate (log-rank test, P=0.0464). Factors affecting residual TR were preoperative TR grade (OR, 7.368; P=0.0267) and mitral valve replacement (OR, 4.369; P=0.0402).

CONCLUSIONS

Late outcome of TAP in the present series was acceptable. Late outcome can be improved by performing TAP before deterioration of TR.

摘要

背景

我们评估了使用柔性带或环进行三尖瓣环成形术(TAP)治疗功能性三尖瓣反流(FTR)后的远期疗效。

方法与结果

我们回顾了2000年1月至2010年12月期间在二尖瓣手术中因FTR接受TAP的220例连续患者(平均年龄65.4±11.4岁)。TAP的适应证包括:(1)三尖瓣反流(TR)分级大于轻度;(2)右心衰竭病史;(3)心房颤动;(4)收缩期肺动脉压(SPAP)≥50 mmHg。平均随访时间为4.4±2.6年。总体医院死亡率为5.5%(12/220)。5年和10年生存率分别为90.2±2.1%和82.4±5.6%。8年时无复发性TR的比例为78.0±6.6%。20例患者在末次随访时TR分级大于轻度。SPAP升高是复发性TR的预测因素(风险比,1.091;P=0.0003),这与高龄、心房颤动、风湿性病因和术前TR分级有关。残余TR大于轻度和小于中度之间在无瓣膜相关事件方面存在显著差异(对数秩检验,P=0.0464)。影响残余TR的因素是术前TR分级(比值比,7.368;P=0.0267)和二尖瓣置换术(比值比,4.369;P=0.0402)。

结论

本系列中TAP的远期疗效是可以接受的。在TR恶化之前进行TAP可改善远期疗效。

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