Fukunaga Naoto, Okada Yukikatsu, Konishi Yasunobu, Murashita Takashi, Koyama Tadaaki
Department of Cardiovascular Surgery, Kobe City Medical Center General Hospital.
Circ J. 2015;79(6):1299-306. doi: 10.1253/circj.CJ-14-1282. Epub 2015 Mar 3.
We assessed late outcome after tricuspid annuloplasty (TAP) using a flexible band or ring for functional tricuspid regurgitation (FTR).
We reviewed 220 consecutive patients (mean age, 65.4±11.4 years) who underwent TAP for FTR during mitral valve surgery between January 2000 and December 2010. Indications for TAP included the following: (1) TR grade greater than mild; (2) history of right heart failure; (3) atrial fibrillation; and (4) systolic pulmonary artery pressure (SPAP) ≥50 mmHg. The mean follow-up period was 4.4±2.6 years. Overall hospital mortality was 5.5% (12/220). The 5- and 10-year survival rates were 90.2±2.1% and 82.4±5.6%, respectively. Freedom from recurrent TR at 8 years was 78.0±6.6%. Twenty patients had a greater than mild TR grade at final follow-up. Elevated SPAP was a predictor of recurrent TR (hazard ratio, 1.091; P=0.0003), which was associated with advanced age, atrial fibrillation, rheumatic etiology and preoperative TR grade. There was a significant difference in freedom from valve-related events between residual TR greater than mild and less than moderate (log-rank test, P=0.0464). Factors affecting residual TR were preoperative TR grade (OR, 7.368; P=0.0267) and mitral valve replacement (OR, 4.369; P=0.0402).
Late outcome of TAP in the present series was acceptable. Late outcome can be improved by performing TAP before deterioration of TR.
我们评估了使用柔性带或环进行三尖瓣环成形术(TAP)治疗功能性三尖瓣反流(FTR)后的远期疗效。
我们回顾了2000年1月至2010年12月期间在二尖瓣手术中因FTR接受TAP的220例连续患者(平均年龄65.4±11.4岁)。TAP的适应证包括:(1)三尖瓣反流(TR)分级大于轻度;(2)右心衰竭病史;(3)心房颤动;(4)收缩期肺动脉压(SPAP)≥50 mmHg。平均随访时间为4.4±2.6年。总体医院死亡率为5.5%(12/220)。5年和10年生存率分别为90.2±2.1%和82.4±5.6%。8年时无复发性TR的比例为78.0±6.6%。20例患者在末次随访时TR分级大于轻度。SPAP升高是复发性TR的预测因素(风险比,1.091;P=0.0003),这与高龄、心房颤动、风湿性病因和术前TR分级有关。残余TR大于轻度和小于中度之间在无瓣膜相关事件方面存在显著差异(对数秩检验,P=0.0464)。影响残余TR的因素是术前TR分级(比值比,7.368;P=0.0267)和二尖瓣置换术(比值比,4.369;P=0.0402)。
本系列中TAP的远期疗效是可以接受的。在TR恶化之前进行TAP可改善远期疗效。