Departments of Cardiac Surgery, National Cerebral and Cardiovascular Center, 6-1 Kishibe-Shinmachi, Suita, Osaka, 564-8565, Japan.
Gen Thorac Cardiovasc Surg. 2024 Dec;72(12):755-762. doi: 10.1007/s11748-024-02033-x. Epub 2024 Apr 22.
Concomitant tricuspid valve (TV) repair is a safe and effective procedure to protect against late moderate or greater tricuspid regurgitation (TR) after left-sided valve surgery, but studies regarding its late outcomes and recurrent TR are limited. This study aimed to reveal the late outcomes and explore the predictors of mortality and recurrent TR among patients who underwent concomitant TV repair with left-sided valve surgery.
This study included 645 patients (mean age, 69.7 years; 44% male) who underwent concomitant TV repair with left-sided valve surgery (mitral valve surgery in 594 cases, aortic valve surgery in 172 cases) from 2006-2020. Preoperative TR was grade 4, 3, and less than 2 in 85, 235, and 325 patients, respectively. The median follow-up period was 4.6 (IQR 1.7-7.8) years. The in-hospital or 30-day mortality was 1.7% (n = 11). Regarding long-term outcomes after TV repair, 90.3% and 80.8% achieved 5- and 10-year survival, respectively, while 96.1% and 88.8% achieved 5- and 10-year freedom from recurrent TR, respectively. The following were independent predictors of overall mortality on multivariate analysis in patients with preoperative TR grade ≥ 3: prior pacemaker implantation, preoperative renal dysfunction, diabetes mellitus and NYHA class ≥ 3. Also, suture annuloplasty and ring type of ring annuloplasty were not independent risk factors for recurrent TR, classified as grade ≥ 3.
Concomitant TV repair with left-sided valve surgery had acceptable outcomes in terms of survival and TR durability. In patients with preoperative TR grade ≥ 3, preoperative patient status had negative impacts on prognosis.
同期三尖瓣(TV)修复术是一种安全有效的方法,可以预防左侧瓣膜手术后晚期中度或重度三尖瓣反流(TR),但关于其晚期结果和复发性 TR 的研究有限。本研究旨在揭示同期 TV 修复术联合左侧瓣膜手术患者的晚期结果,并探讨死亡率和复发性 TR 的预测因素。
本研究纳入了 645 例(平均年龄 69.7 岁;44%为男性)患者,他们在 2006 年至 2020 年期间接受了同期 TV 修复术联合左侧瓣膜手术(594 例二尖瓣手术,172 例主动脉瓣手术)。术前 TR 分级分别为 4 级、3 级和<2 级的患者分别为 85 例、235 例和 325 例。中位随访时间为 4.6(IQR 1.7-7.8)年。院内或 30 天死亡率为 1.7%(n=11)。关于 TV 修复术后的长期结果,90.3%和 80.8%分别获得了 5 年和 10 年的生存率,而 96.1%和 88.8%分别获得了 5 年和 10 年的无复发性 TR 生存率。多变量分析显示,术前 TR 分级≥3 的患者中,以下因素是全因死亡率的独立预测因素:既往起搏器植入、术前肾功能不全、糖尿病和 NYHA 分级≥3。另外,缝线环瓣成形术和环型环瓣成形术不是复发性 TR(分级≥3)的独立危险因素。
同期 TV 修复术联合左侧瓣膜手术在生存率和 TR 耐久性方面具有可接受的结果。在术前 TR 分级≥3 的患者中,术前患者状况对预后有负面影响。