Trindade Ricardo, Albrektsson Tomas, Wennerberg Ann
Department of Prosthodontics, Faculty of Odontology, Malmö University, Carl Gustavsväg 34, 214 21 Malmö, Sweden.
Department of Prosthodontics, Faculty of Odontology, Malmö University, Carl Gustavsväg 34, 214 21 Malmö, Sweden; Department of Biomaterials, Sahlgrenska Academy, Gothenburg University, Arvid Wallgrens backe 20, 413 46 Gothenburg, Sweden.
Oral Maxillofac Surg Clin North Am. 2015 May;27(2):175-83. doi: 10.1016/j.coms.2015.01.004. Epub 2015 Mar 7.
To understand the biological basis of osseointegration, one has to understand the 2 main sides of the implant-host interaction: tissue and biomaterial characteristics. This article addresses osseous tissue characteristics, and the potential role of soft tissues in the osseointegration of dental implants. Successful integration is driven by an inflammatory process. Protein adsorption is key for tissue integration with biomaterials. Osseointegration dynamics relate to the in vivo lifetime of the implant. Understanding this biology is important; it opens the door to putting aside heuristic methods and replaces them by methods that produce solutions to achieve a specific biological goal.
为了解骨结合的生物学基础，必须了解种植体与宿主相互作用的两个主要方面：组织和生物材料特性。本文探讨骨组织特性以及软组织在牙种植体骨结合中的潜在作用。成功的骨结合由炎症过程驱动。蛋白质吸附是组织与生物材料结合的关键。骨结合动力学与种植体的体内使用寿命相关。了解这一生物学知识很重要；它为摒弃启发式方法、代之以能产生实现特定生物学目标解决方案的方法打开了大门。
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