Sahni Sonu, Blood Alexander, Paulus Santhosh, Talwar Arunabh
North Shore - Long Island Jewish Health System, Department of Pulmonary, Critical Care and Sleep Medicine, New York, USA.
Pneumonol Alergol Pol. 2015;83(2):140-3. doi: 10.5603/PiAP.2015.0022.
Spirometry flow-volume loop measurement is the screening test of choice to rule out obstructive lung diseases. Flow oscillations occasionally seen on flow volume loops, referred to as a "saw-tooth" sign, are thought to be due to an upper airway obstructive processes associated with upper airway collapsibility. Widely described in obstructive sleep apnea syndrome, flow oscillations have also been linked to many other upper airway pathologies. The mechanism by which flow oscillations occur is centered on the inspiratory and expiratory flow of air. It has been theorized that the mechanism of flow oscillations result from rapid intermittent changes in driving pressure or airway resistance. Since visual inspection of the flow volume loop can reveal presence of flow oscillations clinicians should be aware of this phenomenon and the presence of flow loop oscillations should clue physicians to rule out upper airway pathology.
肺量计流量-容积环测量是排除阻塞性肺疾病的首选筛查试验。流量容积环上偶尔出现的流量振荡,称为“锯齿”征,被认为是由于与上气道可塌陷性相关的上气道阻塞过程所致。流量振荡在阻塞性睡眠呼吸暂停综合征中已有广泛描述,也与许多其他上气道疾病有关。流量振荡发生的机制集中在吸气和呼气气流上。理论上,流量振荡的机制是由驱动压力或气道阻力的快速间歇性变化引起的。由于对流量容积环的目视检查可以发现流量振荡的存在,临床医生应该意识到这种现象,并且流量环振荡的存在应该提示医生排除上气道病变。