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在一项针对服务不足女性的全国性宫颈癌筛查计划中,针对从未或极少接受筛查的女性进行筛查的有效性。

The effectiveness of targeting never or rarely screened women in a national cervical cancer screening program for underserved women.

作者信息

Benard V B, Royalty J, Saraiya M, Rockwell T, Helsel W

机构信息

Division of Cancer Prevention and Control, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention (CDC), 4770 Buford Highway NE, Mailstop F-76, Atlanta, GA, 30341, USA,

出版信息

Cancer Causes Control. 2015 May;26(5):713-9. doi: 10.1007/s10552-015-0542-3. Epub 2015 Mar 10.

Abstract

PURPOSE

To evaluate the effectiveness of a policy supporting early detection and prevention of cervical cancer among low-income and uninsured women by comparing women who reported never or rarely being screened (last screen >5 years) to those who reported screening in the past ≤5 years.

METHODS

We analyzed data from 1,485,251 women who received their first Pap test in the National Breast and Cervical Cancer Early Detection Program (NBCCEDP) from July 2002 through June 2012. Of these, 461,893 women (31 %) reported being never or rarely screened and 1,023,358 (69 %) reported being screened in the past 5 years. Demographic (age, race/ethnicity, residence, and region) and clinic (cytologic and histologic results) characteristics were examined for the two groups.

RESULTS

Women who were aged ≥50 years, Asian and Pacific Islander, American Indian or Alaska Native, multiracial, living in non-metro areas, or living in the South or a territory were more likely to report being never or rarely screened. The percentage of abnormal Pap tests and the rate of precancer and cancer (combined) was higher in the never or rarely screened group compared with the screened group (abnormal percentage: 2.9 vs 2.6 %, p value < 0.01; rate of precancer and cancer: 6.9 vs 3.7 per 1,000 women, p value < 0.01).

CONCLUSIONS

The priority of reaching never or rarely screened women should continue since those women who entered the NBCCEDP not adequately screened had a greater prevalence of high-grade histological lesions and invasive cervical cancers at later stages than women screened more recently.

摘要

目的

通过比较报告从未或很少接受筛查(上次筛查>5年)的女性与报告过去≤5年接受过筛查的女性,评估一项支持低收入和未参保女性早期发现和预防宫颈癌政策的有效性。

方法

我们分析了2002年7月至2012年6月在国家乳腺癌和宫颈癌早期检测项目(NBCCEDP)中接受首次巴氏试验的1,485,251名女性的数据。其中,461,893名女性(31%)报告从未或很少接受筛查,1,023,358名女性(69%)报告在过去5年接受过筛查。对两组的人口统计学特征(年龄、种族/族裔、居住地和地区)和临床特征(细胞学和组织学结果)进行了检查。

结果

年龄≥50岁、亚裔和太平洋岛民、美洲印第安人或阿拉斯加原住民、多种族、居住在非都市地区或居住在南部或领地的女性更有可能报告从未或很少接受筛查。与筛查组相比,从未或很少接受筛查组的巴氏试验异常百分比以及癌前病变和癌症(合并)发生率更高(异常百分比:2.9%对2.6%,p值<0.01;癌前病变和癌症发生率:每1000名女性中6.9例对3.7例,p值<0.01)。

结论

接触从未或很少接受筛查的女性的工作重点应继续,因为那些进入NBCCEDP时未得到充分筛查的女性,与近期接受筛查的女性相比,晚期高级别组织学病变和浸润性宫颈癌的患病率更高。

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