Thomas C L, Ffolkes L, Akhras V
Department of Dermatology, St George's Hospital, London, UK.
Clin Exp Dermatol. 2015 Oct;40(7):761-4. doi: 10.1111/ced.12622. Epub 2015 Mar 7.
We report the case of a 27-year-old woman presenting with unilateral painless nodules of the left hand following trauma. Initially diagnosed as nontuberculous mycobacterium infection and treated with prolonged courses of antibiotics with little improvement, the condition was subsequently diagnosed histologically as erythema elevatum diutinum (EED). The lesion was treated with surgical excision, and the patient remained lesion-free at the 1-year follow-up. Although the lesion was otherwise asymptomatic, further investigation demonstrated an underlying IgA paraproteinaemia. This case should alert physicians to consider the diagnosis of EED in a unilateral presentation, and highlights the importance of investigation for underlying associated haematological disease.
我们报告了一例27岁女性病例，该患者在手部受伤后出现左手单侧无痛性结节。最初被诊断为非结核分枝杆菌感染，并接受了长时间的抗生素治疗，但改善甚微，随后经组织学诊断为持久性隆起性红斑（EED）。病变通过手术切除进行治疗，患者在1年随访时未再出现病变。尽管该病变无其他症状，但进一步检查发现存在潜在的IgA副蛋白血症。该病例应提醒医生在单侧表现时考虑EED的诊断，并强调对潜在相关血液系统疾病进行检查的重要性。
