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N-乙酰天冬氨酰谷氨酸镁盐治疗急性鼻炎的疗效评估

[Evaluation of the efficacy of the magnesium salt of N-acetyl-aspartyl-glutamic acid in the treatment of acute rhinitis].

作者信息

Miadonna A, Tedeschi A, Parravicini P, Lorini M

出版信息

Clin Ter. 1989 Nov 15;131(3):173-6.

PMID:2575479
Abstract

The object of the above study was to evaluate the tolerability and possible therapeutic use of MgNAAGA (Mg salt of N-acetyl-aspartyl-glutamic acid) in patients with allergic rhinitis. Out of 22 subjects with respiratory allergy, 12 were treated for 15 days with MgNAAGA and 10 with DSCG for the same length of time. During this period, patients kept a diary in which they recorded the following symptoms: rhinorrhea, itching, sneezing and nasal obstruction. The trial drug was found to be well tolerated and not to give rise to relevant side effects. The therapeutic efficacy was similar to that of DSCG.

摘要

上述研究的目的是评估N-乙酰天冬氨酰谷氨酸镁盐(MgNAAGA)在变应性鼻炎患者中的耐受性及可能的治疗用途。在22名呼吸道过敏受试者中,12名用MgNAAGA治疗15天,10名用色甘酸钠(DSCG)治疗相同时长。在此期间,患者记录日记,记下以下症状:鼻漏、瘙痒、打喷嚏和鼻塞。结果发现试验药物耐受性良好,未引起相关副作用。治疗效果与色甘酸钠相似。

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