家蚕利尿激素31受体的鉴定与特性分析
Identification and characterization of the diuretic hormone 31 receptor in the silkworm Bombyx mori.
作者信息
Iga Masatoshi, Kataoka Hiroshi
机构信息
a Department of Integrated Biosciences, Graduate School of Frontier Sciences , The University of Tokyo , Chiba , Japan.
出版信息
Biosci Biotechnol Biochem. 2015;79(8):1305-7. doi: 10.1080/09168451.2015.1018128. Epub 2015 Mar 10.
The receptor for diuretic hormone 31 (DH31R) was identified in the silkworm Bombyx mori. A heterologous expression system revealed that an orphan G-protein coupled receptor, BNGR-B1, responded to DH31 and upregulated the intracellular cAMP level. DH31R (BNGR-B1) was predominantly expressed in the anterior silk gland, midgut, and ovary, whereas DH31 was predominantly expressed in the central nervous system and midgut.
在家蚕中鉴定出利尿激素31（DH31）的受体。一种异源表达系统显示，一种孤儿G蛋白偶联受体BNGR-B1对DH31有反应，并上调细胞内cAMP水平。DH31受体（BNGR-B1）主要在前部丝腺、中肠和卵巢中表达，而DH31主要在中枢神经系统和中肠中表达。
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