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Is low dose hydroxyurea the solution to the global epidemic of sickle cell disease?

作者信息

Strouse John J

机构信息

Department of Pediatrics, Division of Pediatric Hematology, Johns Hopkins University School of Medicine, Baltimore, Maryland; Department of Medicine, Division of Hematology, Johns Hopkins University School of Medicine, Baltimore, Maryland.

出版信息

Pediatr Blood Cancer. 2015 Jun;62(6):929-30. doi: 10.1002/pbc.25471. Epub 2015 Mar 8.

DOI:10.1002/pbc.25471
PMID:25755219
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4405448/
Abstract
摘要

相似文献

1
Is low dose hydroxyurea the solution to the global epidemic of sickle cell disease?低剂量羟基脲是解决镰状细胞病全球流行问题的方法吗?
Pediatr Blood Cancer. 2015 Jun;62(6):929-30. doi: 10.1002/pbc.25471. Epub 2015 Mar 8.
2
Hydroxyurea for sickle-cell anaemia in Africa: mind the gap.非洲镰状细胞贫血的羟基脲治疗:注意差距。
Lancet Glob Health. 2015 Mar;3(3):e124-5. doi: 10.1016/S2214-109X(14)70371-7.
3
Hydroxyurea in very young children with sickle cell anemia is not a cure-all.羟基脲对镰状细胞贫血的幼儿并非万灵药。
J Pediatr. 2001 Dec;139(6):763-4. doi: 10.1067/mpd.2001.120093.
4
Hydroxyurea and sickle cell disease.
Hematol Pathol. 1992;6(4):171-8.
5
Hydroxyurea for sickle cell anemia.羟基脲用于镰状细胞贫血。
N Engl J Med. 2008 Jul 3;359(1):98; author reply 98-9.
6
Hydroxyurea and sickle cell crisis.羟基脲与镰状细胞危象
N Engl J Med. 1995 Oct 12;333(15):1008; author reply 1009. doi: 10.1056/NEJM199510123331514.
7
Hydroxyurea for the treatment of sickle cell anemia.羟基脲用于治疗镰状细胞贫血。
N Engl J Med. 2008 Mar 27;358(13):1362-9. doi: 10.1056/NEJMct0708272.
8
Hydroxyurea and sickle cell crisis.羟基脲与镰状细胞危象
N Engl J Med. 1995 Oct 12;333(15):1008-9.
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Hydroxycarbamide in sickle cell syndrome: new drug. For severe cases only.羟基脲用于镰状细胞综合征:新药。仅用于重症病例。
Prescrire Int. 2009 Feb;18(99):15.
10
[Hydroxyurea treatment in patients affected with sickle cell anemia: efficacy and safety].[羟基脲治疗镰状细胞贫血患者:疗效与安全性]
Transfus Clin Biol. 2008 Feb-Mar;15(1-2):34-8. doi: 10.1016/j.tracli.2008.03.010. Epub 2008 May 21.

引用本文的文献

1
KNOWLEDGE, ATTITUDE AND USE OF HYDROXUYREA AMONG ADULT SICKLE CELL DISEASE PATIENTS.成年镰状细胞病患者对羟基脲的认知、态度及使用情况
Ann Ib Postgrad Med. 2019 Dec;17(2):153-156.
2
Realizing effectiveness across continents with hydroxyurea: Enrollment and baseline characteristics of the multicenter REACH study in Sub-Saharan Africa.在整个非洲大陆实现羟基脲的有效性:多中心 REACH 研究在撒哈拉以南非洲的入组和基线特征。
Am J Hematol. 2018 Aug;93(4):537-545. doi: 10.1002/ajh.25034. Epub 2018 Jan 27.

本文引用的文献

1
Low and fixed dose of hydroxyurea is effective and safe in patients with HbSβ(+) thalassemia with IVS1-5(G→C) mutation.低剂量固定剂量的羟基脲对患有IVS1-5(G→C)突变的HbSβ(+)地中海贫血患者有效且安全。
Pediatr Blood Cancer. 2015 Jun;62(6):1017-23. doi: 10.1002/pbc.25391. Epub 2014 Dec 24.
2
Global, regional, and national age-sex specific all-cause and cause-specific mortality for 240 causes of death, 1990-2013: a systematic analysis for the Global Burden of Disease Study 2013.全球、地区和国家按年龄、性别划分的 240 种死因的全死因和特定死因死亡率,1990-2013 年:2013 年全球疾病负担研究的系统分析。
Lancet. 2015 Jan 10;385(9963):117-71. doi: 10.1016/S0140-6736(14)61682-2. Epub 2014 Dec 18.
3
Reproductive issues in sickle cell disease.镰状细胞病的生殖问题。
Blood. 2014 Dec 4;124(24):3538-43. doi: 10.1182/blood-2014-07-577619.
4
The effect of hydroxyurea on compound heterozygotes for sickle cell-hemoglobin D-Punjab--a single centre experience in eastern India.羟基脲治疗镰状细胞-血红蛋白 D-旁遮普双重杂合子的效果:印度东部单中心经验。
Pediatr Blood Cancer. 2014 Aug;61(8):1341-6. doi: 10.1002/pbc.25004. Epub 2014 Feb 24.
5
Genetic Heterogeneity of Beta Globin Mutations among Asian-Indians and Importance in Genetic Counselling and Diagnosis.亚洲印第安人β珠蛋白基因突变的遗传异质性及其在遗传咨询和诊断中的重要性。
Mediterr J Hematol Infect Dis. 2013;5(1):e2013003. doi: 10.4084/MJHID.2013.003. Epub 2013 Jan 2.
6
Global epidemiology of sickle haemoglobin in neonates: a contemporary geostatistical model-based map and population estimates.全球新生儿镰状细胞血红蛋白病流行病学:基于当代地统计学模型的地图和人群估计。
Lancet. 2013 Jan 12;381(9861):142-51. doi: 10.1016/S0140-6736(12)61229-X. Epub 2012 Oct 25.
7
Low dose hydroxyurea is effective in reducing the incidence of painful crisis and frequency of blood transfusion in sickle cell anemia patients from eastern India.低剂量羟基脲可有效降低印度东部镰状细胞贫血患者疼痛性危象的发生率和输血频率。
Hemoglobin. 2012;36(5):409-20. doi: 10.3109/03630269.2012.709897.
8
High mortality from Plasmodium falciparum malaria in children living with sickle cell anemia on the coast of Kenya.肯尼亚沿海地区镰状细胞贫血儿童感染恶性疟原虫疟疾死亡率高。
Blood. 2010 Sep 9;116(10):1663-8. doi: 10.1182/blood-2010-01-265249. Epub 2010 Jun 8.
9
The effect of prolonged administration of hydroxyurea on morbidity and mortality in adult patients with sickle cell syndromes: results of a 17-year, single-center trial (LaSHS).羟基脲长期治疗对镰状细胞综合征成年患者发病率和死亡率的影响:一项 17 年单中心试验(LaSHS)的结果。
Blood. 2010 Mar 25;115(12):2354-63. doi: 10.1182/blood-2009-05-221333. Epub 2009 Nov 10.
10
Hydroxyurea treatment in children with sickle cell anemia in Central America and the Caribbean countries.中美洲和加勒比国家镰状细胞贫血患儿的羟基脲治疗
Pediatr Blood Cancer. 2006 Jul;47(1):111-2. doi: 10.1002/pbc.20823.