Ludlam H A, Young A E, Berry A J, Phillips I
Department of Medical Microbiology, St. Thomas' Hospital, London, UK.
J Hosp Infect. 1989 Nov;14(4):293-301. doi: 10.1016/0195-6701(89)90069-8.
We describe the control of wound infection with Staphylococcus aureus in patients undergoing continuous ambulatory peritoneal dialysis at St. Thomas' Hospital. Forty-nine percent of 61 catheters inserted in 1985 and 1986 became infected, and the majority of these infections were acquired in hospital. Infection was impossible to eradicate and was frequently associated with the subsequent development of S. aureus peritonitis, which was the most important cause of catheter loss. Strict adherence to aseptic techniques for catheter insertion and care, combined with eradication of S. aureus carriage, reduced the infection rate to 12% for the 50 catheters inserted in 1987, abolished hospital-acquired infection and reduced the S. aureus peritonitis rate tenfold, without the use of prophylactic antibiotics. S. aureus infection is a serious but avoidable complication of continuous ambulatory peritoneal dialysis.
我们描述了圣托马斯医院接受持续性非卧床腹膜透析患者金黄色葡萄球菌伤口感染的控制情况。1985年和1986年插入的61根导管中有49%发生了感染，且这些感染大多是在医院获得的。感染难以根除，且常与随后发生的金黄色葡萄球菌性腹膜炎相关，后者是导管丢失的最重要原因。严格遵守导管插入和护理的无菌技术，结合根除金黄色葡萄球菌携带情况，使得1987年插入的50根导管的感染率降至12%，消除了医院获得性感染，并使金黄色葡萄球菌性腹膜炎的发生率降低了十倍，且未使用预防性抗生素。金黄色葡萄球菌感染是持续性非卧床腹膜透析的一种严重但可避免的并发症。
