Sumesh Remani Vasudevan, Malathi Akilan, Ranjith Kumar Raju
Department of Organic Chemistry, School of Chemistry, Madurai Kamaraj University, Madurai, 625 021, Tamil Nadu, India.
Mol Divers. 2015 May;19(2):233-49. doi: 10.1007/s11030-015-9576-4. Epub 2015 Mar 11.
A facile and efficient synthesis of a library of novel chromeno[3,2-c]pyridines has been achieved from the reaction of various 3,5-((E)-arylidene)-1-alkylpiperidin-4-ones and cyclic 1,3-diketones. The reaction presumably occurred via tandem Michael addition-intramolecular O-cyclization-elimination sequence in a single operation.
通过各种3,5-（（E）-亚芳基）-1-烷基哌啶-4-酮与环状1,3-二酮的反应，实现了一系列新型色烯并[3,2-c]吡啶的简便高效合成。该反应可能通过串联迈克尔加成-分子内O-环化-消除序列在一步操作中发生。
