口腔源性菌血症与远处感染之间的关联：刷牙与单颗牙齿拔除。
Associations between bacteremia from oral sources and distant-site infections: tooth brushing versus single tooth extraction.
作者信息
Mougeot Farah K Bahrani, Saunders Sabrina E, Brennan Michael T, Lockhart Peter B
机构信息
Director of Oral Medicine Laboratory, Department of Oral Medicine, Carolinas Medical Center, Charlotte, NC, USA.
Cannon Research Summer Scholar, Department of Oral Medicine, Carolinas Medical Center, Charlotte, NC, USA.
出版信息
Oral Surg Oral Med Oral Pathol Oral Radiol. 2015 Apr;119(4):430-5. doi: 10.1016/j.oooo.2015.01.009. Epub 2015 Feb 3.
OBJECTIVES
To determine the impact of antibiotic prophylaxis (AP) on the incidence of bacteremia caused by oral bacterial species associated with infective endocarditis (IE) and prosthetic joint infections (PJIs) and to compare the incidence of following tooth brushing versus single tooth extraction.
STUDY DESIGN
Bacterial species in blood following single tooth extraction, with or without AP, and tooth brushing(1) were compared with IE- and PJI-associated bacteria reported in the literature.
RESULTS
Of the 98 bacterial species identified in blood following single tooth extraction and tooth brushing, 32(1) and 12 were species were associated with IE and PJI, respectively. AP decreased the frequency of IE- and PJI-causing oral bacterial species in blood; however, single tooth extraction versus brushing resulted in bacteremia with IE- and PJI-causing species with similar frequencies: 65% versus 56% for IE, and 31% versus 28% for PJI.
CONCLUSIONS
Although AP significantly decreased the incidence of bacteremia, the similarity between the incidence of bacteremia following brushing and extraction undermines AP as an effective strategy for the prevention of these distant-site infections.
目的
确定抗生素预防（AP）对由与感染性心内膜炎（IE）和人工关节感染（PJI）相关的口腔细菌种类引起的菌血症发生率的影响，并比较刷牙与单颗牙拔除后菌血症的发生率。
研究设计
将单颗牙拔除后（无论有无AP）及刷牙后的血液中的细菌种类与文献报道的与IE和PJI相关的细菌进行比较。
结果
在单颗牙拔除和刷牙后的血液中鉴定出的98种细菌中，分别有32种和12种与IE和PJI相关。AP降低了血液中引起IE和PJI的口腔细菌种类的频率；然而，单颗牙拔除与刷牙导致菌血症的频率相似，引起IE的细菌种类分别为65%和56%，引起PJI的细菌种类分别为31%和28%。
结论
虽然AP显著降低了菌血症的发生率，但刷牙和拔牙后菌血症发生率的相似性削弱了AP作为预防这些远处感染的有效策略的作用。
Zotero 插件