猪繁殖与呼吸综合征病毒的结构、复制及重组：表型与基因型多样性的起源
PRRSV structure, replication and recombination: Origin of phenotype and genotype diversity.
作者信息
Kappes Matthew A, Faaberg Kay S
机构信息
Virus and Prion Research Unit, USDA-ARS-National Animal Disease Center, Ames, IA, USA.
Virus and Prion Research Unit, USDA-ARS-National Animal Disease Center, Ames, IA, USA.
出版信息
Virology. 2015 May;479-480:475-86. doi: 10.1016/j.virol.2015.02.012. Epub 2015 Mar 7.
Porcine reproductive and respiratory disease virus (PRRSV) has the intrinsic ability to adapt and evolve. After 25 years of study, this persistent pathogen has continued to frustrate efforts to eliminate infection of herds through vaccination or other elimination strategies. The purpose of this review is to summarize the research on the virion structure, replication and recombination properties of PRRSV that have led to the extraordinary phenotype and genotype diversity that exists worldwide.
猪繁殖与呼吸综合征病毒（PRRSV）具有内在的适应和进化能力。经过25年的研究，这种持续性病原体通过疫苗接种或其他根除策略来消除猪群感染的努力仍一直受挫。本综述的目的是总结关于PRRSV病毒粒子结构、复制和重组特性的研究，这些研究导致了全球范围内存在的异常表型和基因型多样性。
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