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核心技术专利：CN118964589B侵权必究

核心技术专利：CN118964589B侵权必究

Tonosaki K, Funakoshi M

Department of Oral Physiology, School of Dentistry, Asahi University, Gifu, Japan.

Comp Biochem Physiol A Comp Physiol. 1989;94(4):659-61.

The receptor potential of the mouse taste cell was recorded with an intracellular microelectrode while taste stimuli were applied to the tongue surface of the anesthetized mouse. 2. A membrane depolarization accompanied by an increase in membrane resistance was observed after a sucrose stimulus. 3. A sodium-chloride stimulus initiated a membrane depolarization accompanied by a decrease in membrane resistance. 4. Amiloride elicits a depolarization of the membrane and is accompanied by an increase in membrane resistance. 5. Pre-adapting the tongue to amiloride, which is known as a potent sodium channel blocker, did not alter the responses to sodium-chloride and other taste stimuli.

在对麻醉的小鼠舌面施加味觉刺激时，用细胞内微电极记录小鼠味觉细胞的感受器电位。2. 蔗糖刺激后观察到膜去极化并伴有膜电阻增加。3. 氯化钠刺激引发膜去极化并伴有膜电阻降低。4. 氨氯吡咪引起膜去极化并伴有膜电阻增加。5. 预先用已知为强效钠通道阻滞剂的氨氯吡咪处理舌头，并未改变对氯化钠及其他味觉刺激的反应。

Tonosaki K, Funakoshi M

Department of Oral Physiology, School of Dentistry, Asahi University, Gifu, Japan.

Comp Biochem Physiol A Comp Physiol. 1989;94(4):659-61.

The receptor potential of the mouse taste cell was recorded with an intracellular microelectrode while taste stimuli were applied to the tongue surface of the anesthetized mouse. 2. A membrane depolarization accompanied by an increase in membrane resistance was observed after a sucrose stimulus. 3. A sodium-chloride stimulus initiated a membrane depolarization accompanied by a decrease in membrane resistance. 4. Amiloride elicits a depolarization of the membrane and is accompanied by an increase in membrane resistance. 5. Pre-adapting the tongue to amiloride, which is known as a potent sodium channel blocker, did not alter the responses to sodium-chloride and other taste stimuli.

在对麻醉的小鼠舌面施加味觉刺激时，用细胞内微电极记录小鼠味觉细胞的感受器电位。2. 蔗糖刺激后观察到膜去极化并伴有膜电阻增加。3. 氯化钠刺激引发膜去极化并伴有膜电阻降低。4. 氨氯吡咪引起膜去极化并伴有膜电阻增加。5. 预先用已知为强效钠通道阻滞剂的氨氯吡咪处理舌头，并未改变对氯化钠及其他味觉刺激的反应。