Department of Urology, Trakya University Faculty of Medicine, Edirne, Turkey.
Department of Pathology, Trakya University Faculty of Medicine, Edirne, Turkey.
Balkan Med J. 2015 Jan;32(1):114-7. doi: 10.5152/balkanmedj.2015.15053. Epub 2015 Jan 1.
Urachal masses observed in adults should be considered malignant unless they are confuted. It is very difficult to differentiate between malignant or benign lesions, including especially calcified foci and solid areas.
Our case was a 63-year-old male patient who was diagnosed as Behçet's Disease 26 years ago. Upon clinical examination, he was also diagnosed with adenocarcinoma of prostate. He was examined by computerized tomography to define the stage of prostatic adenocarcinoma. The existence of a hypodense multiseptated cystic lesion with irregular margins and solid areas located between anterosuperior of bladder and umbilicus was reported. Hence, the lesion was evaluated as urachal carcinoma and locally advanced prostate cancer by the urooncology council. Resection of the mass, partial cystectomy and pelvic lymphadenectomy were performed as one of the surgical approach options in urachal carcinoma. After pathological examination, the mass was diagnosed as malakoplakia and metastasis of prostate adenocarcinoma was also detected in the right obdurator lymph nodule. In the literature, case reports of urachal malakoplakia are extremely rare. It is also interesting to note the absence of specific clinical symptoms for the urachal mass and the existence of concomitant adenocarcinoma in our case.
Malakoplakia can only be diagnosed by pathological examination. Particularly, urachal malakoplakia should also be taken into consideration in the differential diagnosis of lesions which include solid areas and are located in the urachus.
成人中观察到的脐尿管肿块应被视为恶性肿瘤,除非有证据证明其为良性。要区分良恶性病变非常困难,包括特别是钙化灶和实性区域。
我们的病例是一位 63 岁的男性患者,他在 26 年前被诊断为贝切特病。临床检查还诊断他患有前列腺腺癌。他接受了计算机断层扫描检查,以确定前列腺腺癌的分期。报告称,在膀胱前上和脐之间存在一个低密多孔性囊性病变,边缘不规则,有实性区域。因此,尿路肿瘤委员会将病变评估为脐尿管癌和局部晚期前列腺癌。作为脐尿管癌的一种手术方法选择,进行了肿块切除、部分膀胱切除术和盆腔淋巴结切除术。病理检查后,该肿块被诊断为类脂性肉芽肿病,并且在右侧闭孔淋巴结中还检测到前列腺腺癌转移。在文献中,脐尿管类脂性肉芽肿病的病例报告极为罕见。值得注意的是,我们的病例中脐部肿块没有特定的临床症状,并且存在同时发生的腺癌。
只有通过病理检查才能诊断类脂性肉芽肿病。特别是在位于脐尿管的包含实性区域的病变的鉴别诊断中,也应考虑到脐尿管类脂性肉芽肿病。