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脐尿管软斑病病例,类似脐尿管癌。

A Case of Urachal Malacoplakia that Seems Like Urachal Cancer.

机构信息

Department of Urology, Trakya University Faculty of Medicine, Edirne, Turkey.

Department of Pathology, Trakya University Faculty of Medicine, Edirne, Turkey.

出版信息

Balkan Med J. 2015 Jan;32(1):114-7. doi: 10.5152/balkanmedj.2015.15053. Epub 2015 Jan 1.

DOI:10.5152/balkanmedj.2015.15053
PMID:25759783
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4342124/
Abstract

BACKGROUND

Urachal masses observed in adults should be considered malignant unless they are confuted. It is very difficult to differentiate between malignant or benign lesions, including especially calcified foci and solid areas.

CASE REPORT

Our case was a 63-year-old male patient who was diagnosed as Behçet's Disease 26 years ago. Upon clinical examination, he was also diagnosed with adenocarcinoma of prostate. He was examined by computerized tomography to define the stage of prostatic adenocarcinoma. The existence of a hypodense multiseptated cystic lesion with irregular margins and solid areas located between anterosuperior of bladder and umbilicus was reported. Hence, the lesion was evaluated as urachal carcinoma and locally advanced prostate cancer by the urooncology council. Resection of the mass, partial cystectomy and pelvic lymphadenectomy were performed as one of the surgical approach options in urachal carcinoma. After pathological examination, the mass was diagnosed as malakoplakia and metastasis of prostate adenocarcinoma was also detected in the right obdurator lymph nodule. In the literature, case reports of urachal malakoplakia are extremely rare. It is also interesting to note the absence of specific clinical symptoms for the urachal mass and the existence of concomitant adenocarcinoma in our case.

CONCLUSION

Malakoplakia can only be diagnosed by pathological examination. Particularly, urachal malakoplakia should also be taken into consideration in the differential diagnosis of lesions which include solid areas and are located in the urachus.

摘要

背景

成人中观察到的脐尿管肿块应被视为恶性肿瘤,除非有证据证明其为良性。要区分良恶性病变非常困难,包括特别是钙化灶和实性区域。

病例报告

我们的病例是一位 63 岁的男性患者,他在 26 年前被诊断为贝切特病。临床检查还诊断他患有前列腺腺癌。他接受了计算机断层扫描检查,以确定前列腺腺癌的分期。报告称,在膀胱前上和脐之间存在一个低密多孔性囊性病变,边缘不规则,有实性区域。因此,尿路肿瘤委员会将病变评估为脐尿管癌和局部晚期前列腺癌。作为脐尿管癌的一种手术方法选择,进行了肿块切除、部分膀胱切除术和盆腔淋巴结切除术。病理检查后,该肿块被诊断为类脂性肉芽肿病,并且在右侧闭孔淋巴结中还检测到前列腺腺癌转移。在文献中,脐尿管类脂性肉芽肿病的病例报告极为罕见。值得注意的是,我们的病例中脐部肿块没有特定的临床症状,并且存在同时发生的腺癌。

结论

只有通过病理检查才能诊断类脂性肉芽肿病。特别是在位于脐尿管的包含实性区域的病变的鉴别诊断中,也应考虑到脐尿管类脂性肉芽肿病。

相似文献

1
A Case of Urachal Malacoplakia that Seems Like Urachal Cancer.脐尿管软斑病病例,类似脐尿管癌。
Balkan Med J. 2015 Jan;32(1):114-7. doi: 10.5152/balkanmedj.2015.15053. Epub 2015 Jan 1.
2
Isolated urachal malakoplakia mimicking malignancy.孤立性脐尿管软斑症酷似恶性肿瘤。
Urol Ann. 2017 Jan-Mar;9(1):92-95. doi: 10.4103/0974-7796.198900.
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[Microscopic foci of urachal carcinoma in an incidentally detected urachal cyst: a case report].[偶然发现的脐尿管囊肿中脐尿管癌的微小病灶:一例报告]
Hinyokika Kiyo. 1997 Oct;43(10):731-3.
4
[Urachal mass in adults: clinical analysis of 33 cases].[成人脐尿管肿物:33例临床分析]
Zhonghua Yi Xue Za Zhi. 2008 Mar 25;88(12):820-2.
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Urachal urothelial carcinoma diagnosed at a radical prostatectomy operation: a case report.根治性前列腺切除术中诊断出的脐尿管尿路上皮癌:一例报告
Anal Quant Cytol Histol. 2010 Jun;32(3):174-7.
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En Bloc Robot-assisted Laparoscopic Partial Cystectomy, Urachal Resection, and Pelvic Lymphadenectomy for Urachal Adenocarcinoma.整块机器人辅助腹腔镜下膀胱部分切除术、脐尿管切除术及盆腔淋巴结清扫术治疗脐尿管腺癌
Rev Urol. 2015;17(1):46-9.
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Laparoscopic en bloc partial cystectomy with bilateral pelvic lymphadenectomy for urachal adenocarcinoma.腹腔镜整块部分膀胱切除术联合双侧盆腔淋巴结清扫术治疗脐尿管腺癌
Urology. 2006 Apr;67(4):837-43. doi: 10.1016/j.urology.2005.10.048.
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Calcified Urachal Cancer Managed by Partial Cystectomy: A Case Report.经部分膀胱切除术治疗的钙化脐尿管癌:一例报告
Res Rep Urol. 2021 Oct 7;13:745-748. doi: 10.2147/RRU.S330765. eCollection 2021.
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Urachal abnormalities: clinical and imaging features.脐尿管异常:临床与影像学特征
Singapore Med J. 2008 Nov;49(11):930-5.
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[Early urachal carcinoma diagnosed by magnetic resonance imaging: a case report].[磁共振成像诊断早期脐尿管癌:一例报告]
Hinyokika Kiyo. 1997 Jan;43(1):57-9.

引用本文的文献

1
Bladder malacoplakia: A case report.膀胱软斑症:一例报告。
World J Clin Cases. 2022 Aug 16;10(23):8291-8297. doi: 10.12998/wjcc.v10.i23.8291.
2
No significant risk of secondary prostatic cancer in a patient with prostatic malakoplakia after a four-year follow-up.一名前列腺软斑病患者经过四年随访后,发生继发性前列腺癌的风险不显著。
Int J Clin Exp Pathol. 2018 Aug 1;11(8):4153-4157. eCollection 2018.
3
Biomarkers in Urachal Cancer and Adenocarcinomas in the Bladder: A Comprehensive Review Supplemented by Own Data.脐尿管癌和膀胱腺癌的生物标志物:综述补充自有数据。
Dis Markers. 2018 Mar 12;2018:7308168. doi: 10.1155/2018/7308168. eCollection 2018.
4
Isolated urachal malakoplakia mimicking malignancy.孤立性脐尿管软斑症酷似恶性肿瘤。
Urol Ann. 2017 Jan-Mar;9(1):92-95. doi: 10.4103/0974-7796.198900.

本文引用的文献

1
Isolated Malacoplakia of the bladder: a rare case report and review of literature.孤立性膀胱软斑症:一例罕见病例报告及文献复习
Int Urol Nephrol. 2010 Jun;42(2):349-50. doi: 10.1007/s11255-009-9624-z. Epub 2009 Aug 8.
2
[Urachal mass in adults: clinical analysis of 33 cases].[成人脐尿管肿物:33例临床分析]
Zhonghua Yi Xue Za Zhi. 2008 Mar 25;88(12):820-2.
3
Population based survival data on urachal tumors.基于人群的脐尿管肿瘤生存数据。
J Urol. 2006 Jun;175(6):2042-7; discussion 2047. doi: 10.1016/S0022-5347(06)00263-1.
4
[Malacoplakia in children].[儿童软斑病]
Prog Urol. 2005 Jun;15(3):511-3.
5
Computed tomographic appearance of urachal adenocarcinomas: review of 25 cases.脐尿管腺癌的计算机断层扫描表现:25例病例回顾
Eur Radiol. 2005 Jan;15(1):79-84. doi: 10.1007/s00330-004-2408-z. Epub 2004 Jul 17.
6
Urachal carcinoma: the case for extended partial cystectomy.脐尿管癌:扩大性部分膀胱切除术的病例分析
J Urol. 1994 Feb;151(2):365-6. doi: 10.1016/s0022-5347(17)34950-9.