Jarrot P A, Leone J, Brochot P, Pennaforte J L
Department of Internal Medicine, Reference Center for Systemic Lupus Erythematosus Management ("Centre de compétence des maladies auto-immunes et systémiques"), Hôpital Robert Debré, Centre Hospitalier Universitaire de Reims (CHU), France
Department of Internal Medicine, Reference Center for Systemic Lupus Erythematosus Management ("Centre de compétence des maladies auto-immunes et systémiques"), Hôpital Robert Debré, Centre Hospitalier Universitaire de Reims (CHU), France.
Lupus. 2015 Oct;24(12):1318-20. doi: 10.1177/0961203315576590. Epub 2015 Mar 11.
Except for traumatic and iatrogenic causes, Achilles tendinitis (AT) is mostly encountered in the context of inflammatory rheumatic diseases. This study aimed to describe AT in systemic lupus erythematosus (SLE).
Among 158 SLE patients who fulfilled the SLE criteria of the ACR classification followed between 1980 and 2013, we selected those who experienced at least one episode of AT not caused by traumatic or toxicity factors.
Eight patients (one male, seven females), median age 52 years (range: 35-68), presented with 11 episodes of AT within an average of 10.5 (0-21) years after SLE diagnosis. Clinical presentation of SLE was mainly cutaneous (eight of eight), and articular (seven of eight). Axial symptoms were reported in six patients, two of whom had HLA-B27-positive status, and fulfilled the Amor and European Spondylarthropathy Study Group criteria. Resolution of AT was good with nonsteroidal anti-inflammatory topical or systemic drug therapies, which kept SLE quiescent and avoided any increase of specific treatment.
Although the association is rare, when AT occurs in SLE patients, physicians should look for associated spondylarthritis.
除创伤性和医源性原因外，跟腱炎（AT）大多在炎性风湿性疾病背景下出现。本研究旨在描述系统性红斑狼疮（SLE）中的跟腱炎。
在1980年至2013年随访的158例符合美国风湿病学会（ACR）分类SLE标准的患者中，我们选取了那些经历过至少一次非创伤性或毒性因素引起的跟腱炎发作的患者。
8例患者（1例男性，7例女性），中位年龄52岁（范围：35 - 68岁），在SLE诊断后平均10.5（0 - 21）年出现11次跟腱炎发作。SLE的临床表现主要为皮肤型（8例中的8例）和关节型（8例中的7例）。6例患者有轴向症状，其中2例HLA - B27呈阳性，符合Amor和欧洲脊柱关节病研究组标准。非甾体类抗炎局部或全身药物治疗使跟腱炎好转，且使SLE保持静止，避免了特定治疗的增加。
尽管这种关联罕见，但当SLE患者出现跟腱炎时，医生应寻找相关的脊柱关节炎。
