[与囊性纤维化基因相关的多态性研究中的DNA扩增]
[DNA amplification in the study of polymorphisms linked to the cystic fibrosis gene].
作者信息
Claustres M, Bellet H, Desgeorges M, Kjellberg P, Toueri M F, Rollin B, Bonnet H
出版信息
J Genet Hum. 1989 Sep;37(3):243-9.
PMID:2576281
Abstract
The highly specific polymerase chain reaction recently described can be used to amplify selectively several polymorphic regions of DNA genetically close to the cystic fibrosis gene. This method, providing automated, revolutionizes the classical methods of prenatal diagnosis and carrier detection.
摘要
最近描述的高特异性聚合酶链反应可用于选择性扩增与囊性纤维化基因遗传距离相近的几个DNA多态性区域。这种方法实现了自动化，彻底改变了传统的产前诊断和携带者检测方法。
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