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[DNA amplification in the study of polymorphisms linked to the cystic fibrosis gene].

作者信息

Claustres M, Bellet H, Desgeorges M, Kjellberg P, Toueri M F, Rollin B, Bonnet H

出版信息

J Genet Hum. 1989 Sep;37(3):243-9.

PMID:2576281
Abstract

The highly specific polymerase chain reaction recently described can be used to amplify selectively several polymorphic regions of DNA genetically close to the cystic fibrosis gene. This method, providing automated, revolutionizes the classical methods of prenatal diagnosis and carrier detection.

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