Shin Gi Won, Jeong Hae Woong
Department of Diagnostic Radiology, Busan Paik Hospital, Inje University, Busan, Korea.
Neurointervention. 2015 Feb;10(1):14-21. doi: 10.5469/neuroint.2015.10.1.14. Epub 2015 Feb 28.
To report angiographic and clinical results of endovascular treatment in 45 intracranial vertebral artery dissecting aneurysms (VADAs).
From July 2002 to September 2013, a total of 42 patients with 45 VADAs received endovascular treatment. Endovascular treatment consisted of internal trapping with detachable coils, stent-assisted coiling, and stenting only. Immediate and follow-up angiographic findings and clinical outcome were retrospectively reviewed.
There were 17 ruptured VADAs and 28 unruptured VADAs. Overall, 26 VADAs were treated with internal trapping, 14 with stent-assisted coil embolization, and 5 with stenting only. Immediate angiographic results revealed complete occlusion in 31 cases and incomplete occlusion in 14 cases. Follow-up imaging studies were available in 31 cases. On follow-up imaging, antegrade recanalization occurred in 2 of 16 cases treated with internal trapping. Aneurysmal recurrence occurred in one case treated with stent-assisted coiling. Procedural complications occurred in 8 patients. In cases of unruptured VADA, favorable outcome (mRS 0 and 1) was achieved in 26 cases and poor outcome (mRS 2-5) in 2 cases. There was no mortality in patients with unruptured VADAs.
Endovascular treatment of intracranial VADA appears to be safe and effective. Follow-up angiographic study is needed because parent artery recanalization or aneurysmal recurrence can occur.
报告45例颅内椎动脉夹层动脉瘤(VADA)血管内治疗的血管造影结果及临床疗效。
2002年7月至2013年9月,共42例患有45个VADA的患者接受了血管内治疗。血管内治疗包括用可脱卸弹簧圈进行血管内闭塞、支架辅助弹簧圈栓塞以及单纯支架置入。回顾性分析即刻及随访血管造影结果和临床结局。
有17个破裂的VADA和28个未破裂的VADA。总体而言,26个VADA采用血管内闭塞治疗,14个采用支架辅助弹簧圈栓塞治疗,5个仅采用支架置入治疗。即刻血管造影结果显示31例完全闭塞,14例不完全闭塞。31例患者有随访影像学检查结果。在随访影像学检查中,16例采用血管内闭塞治疗的患者中有2例出现顺行再通。1例采用支架辅助弹簧圈栓塞治疗的患者出现动脉瘤复发。8例患者发生手术并发症。在未破裂VADA的病例中,26例取得良好结局(改良Rankin量表评分0和1),2例结局不佳(改良Rankin量表评分2 - 5)。未破裂VADA患者无死亡病例。
颅内VADA的血管内治疗似乎安全有效。由于可能发生载瘤动脉再通或动脉瘤复发,需要进行随访血管造影研究。