Piplani Sanjay, Mannan Rahul, Lalit Monika, Manjari Mridu, Bhasin Tejinder S, Bawa Jasmin
Department of Pathology, Sri Guru Ram Das Institute of Medical Sciences & Research, 24 Lane No. 5, Gopal Nagar, Majitha Road, Amritsar, Punjab 143001, India.
Department of Anatomy, Sri Guru Ram Das Institute of Medical Sciences & Research, Amritsar, Punjab, India.
Anal Cell Pathol (Amst). 2014;2014:343461. doi: 10.1155/2014/343461. Epub 2014 Nov 25.
Thoracic lesions account for various benign and malignant conditions. Of these lung carcinoma (mainly primary) is the most common carcinoma in the world. The present study was undertaken to know the pathological spectrum of thoracic lesions and to correlate cytoradiological findings.
The present study was conducted in a tertiary care center of North India on 74 patients over an 18-month period. CT guided transthoracic FNAC (TTFNA) was carried out, and aspirates were drawn, examined, and compared with radiological diagnoses.
The diagnostic accuracy for FNA in the present study was calculated to be 95.94% (using cytology as the gold standard). The predominant lesion was malignancy (85.1%), followed by suspicions of malignancy and inflammatory pathology (5.40% each). By cytology, the most common malignant lesion was adenocarcinoma (48%) followed by squamous cell carcinoma (40%), small cell carcinoma (8%), and undifferentiated carcinoma (4%). Cytoradiological correlation was found to be 89.2% in the present study.
Present study thus concludes that TT FNA of thoracic lesions is a simple, safe, economically prudent technique associated with low morbidity and leading to quick and early diagnosis.
胸部病变涵盖多种良性和恶性疾病。其中肺癌(主要是原发性肺癌)是全球最常见的癌症。本研究旨在了解胸部病变的病理谱,并将细胞放射学检查结果进行关联分析。
本研究在印度北部一家三级医疗中心对74例患者进行了为期18个月的研究。进行了CT引导下经胸细针穿刺抽吸活检(TTFNA),抽取抽吸物,进行检查,并与放射学诊断结果进行比较。
本研究中FNA的诊断准确率经计算为95.94%(以细胞学检查作为金标准)。主要病变为恶性肿瘤(85.1%),其次是疑似恶性肿瘤和炎症性病变(各占5.40%)。通过细胞学检查,最常见的恶性病变是腺癌(48%),其次是鳞状细胞癌(40%)、小细胞癌(8%)和未分化癌(4%)。本研究中细胞放射学关联率为89.2%。
本研究因此得出结论,胸部病变的TT FNA是一种简单、安全、经济实惠的技术,发病率低,能实现快速早期诊断。