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计算机断层扫描引导下肺肿块病变的细针穿刺细胞学检查:我们的经验。

Computed tomography guided fine needle aspiration cytology of mass lesions of lung: Our experience.

作者信息

Gangopadhyay Mimi, Chakrabarti Indranil, Ghosh Nilanjana, Giri Amita

机构信息

Department of Pathology, North Bengal Medical College, Sushrutanagar, Darjeeling, West Bengal, India.

出版信息

Indian J Med Paediatr Oncol. 2011 Oct;32(4):192-6. doi: 10.4103/0971-5851.95139.

Abstract

CONTEXT

Computerized tomography (CT) guided fine needle aspiration cytology (FNAC) of lung lesions has rapidly emerged as a less-invasive, cheap, rapid and fairly accurate diagnostic aid in lung lesions.

AIMS

The purpose of this present study was to evaluate the effectiveness of CT-guided FNAC in the diagnosis of pulmonary mass lesions (both benign and malignant) and to determine the complication rate of this procedure.

SETTINGS AND DESIGN

We conducted an institution-based, prospective study on 127 patients who presented with pulmonary mass lesions.

MATERIALS AND METHODS

After proper consent was obtained, CT-guided transthoracic fine needle aspiration was done and their diagnoses were confirmed by appropriate methods. The results were analyzed statistically.

RESULTS

Out of 127 cases selected for the study, 59.8% were males while the rest were females. Cough was the most common symptom present in 71.2% cases, followed by weight loss (62.4%). 21.2% cases were cytologically benign. Adenocarcinoma (54.2%) was the commonest malignant tumor. FNAC provided at least 96% sensitivity and 100% specificity in diagnosing lung tumors. Among the benign lesions, specific diagnoses were obtained in 48.1% cases. Thus, altogether a specific diagnosis was obtained in 109 of 127 cases, i.e. 85.8%. No major complication was noted.

CONCLUSIONS

CT-guided FNAC is an extremely valuable and fairly accurate diagnostic aid of intrathoracic mass lesions, with a reasonable rate of complication.

摘要

背景

计算机断层扫描(CT)引导下肺病变细针穿刺抽吸细胞学检查(FNAC)已迅速成为一种侵入性较小、价格低廉、快速且相当准确的肺病变诊断辅助手段。

目的

本研究的目的是评估CT引导下FNAC在诊断肺部肿块病变(包括良性和恶性)中的有效性,并确定该操作的并发症发生率。

设置与设计

我们对127例出现肺部肿块病变的患者进行了一项基于机构的前瞻性研究。

材料与方法

在获得适当同意后,进行CT引导下经胸细针抽吸,并通过适当方法确诊。对结果进行统计学分析。

结果

在入选研究的127例病例中,59.8%为男性,其余为女性。咳嗽是最常见症状,占71.2%的病例,其次是体重减轻(62.4%)。21.2%的病例细胞学检查为良性。腺癌(54.2%)是最常见的恶性肿瘤。FNAC在诊断肺部肿瘤方面提供了至少96%的敏感性和100%的特异性。在良性病变中,48.1%的病例获得了明确诊断。因此,127例病例中有109例(即85.8%)获得了明确诊断。未观察到重大并发症。

结论

CT引导下FNAC是一种极其有价值且相当准确的胸内肿块病变诊断辅助手段,并发症发生率合理。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1811/3343244/ac92ba196463/IJMPO-32-192-g003.jpg

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