Adiga Prashanth, Kantharaja Indumathi, Hebbar Shripad, Rai Lavanya, Guruvare Shyamala, Mundkur Anjali
Department of Obstetrics and Gynaecology, Kasturba Medical College, Manipal University, Manipal 576104, India.
Int J Reprod Med. 2015;2015:614747. doi: 10.1155/2015/614747. Epub 2015 Feb 1.
Aims and Objectives. (i) To determine the predictive value of cerebrouterine (CU) ratio (middle cerebral artery to uterine artery pulsatility index, MCA/UT PI) in assessing perinatal outcome among hypertensive disorders of pregnancy. (ii) To compare between CU ratio and CP ratio (MCA/Umbilical artery PI) as a predictor of adverse perinatal outcome. Methods. A prospective observational study was done in a tertiary medical college hospital, from September 2012 to August 2013. One hundred singleton pregnancies complicated by hypertension peculiar to pregnancy were enrolled. Both CU and CP ratios were estimated. The perinatal outcomes were studied. Results. Both cerebrouterine and cerebroplacental ratios had a better negative predictive value in predicting adverse perinatal outcome. However, both CU and CP ratios when applied together were able to predict adverse outcomes better than individual ratios. The sensitivity, specificity, positive predictive value, and the negative predictive values for an adverse neonatal outcome with CU ratio were 61.3%, 70.3%, 56%, and 78.9%, respectively, compared to 42%, 57.5%, 62%, and 76% as with CP ratio. Conclusion. Cerebrouterine ratio and cerebroplacental ratio were complementary to each other in predicting the adverse perinatal outcomes. Individually, both ratios were reassuring for favorable perinatal outcome with high negative predictive value.
目的。（i）确定脑-子宫（CU）比值（大脑中动脉与子宫动脉搏动指数，MCA/UT PI）在评估妊娠高血压疾病围产期结局中的预测价值。（ii）比较CU比值和脑-胎盘比值（MCA/脐动脉PI）作为围产期不良结局预测指标的差异。方法。2012年9月至2013年8月在一所三级医学院附属医院进行了一项前瞻性观察研究。纳入100例单胎妊娠合并妊娠特发性高血压的孕妇。同时评估CU和CP比值。对围产期结局进行研究。结果。脑-子宫和脑-胎盘比值在预测围产期不良结局方面均具有较好的阴性预测价值。然而，将CU和CP比值联合应用时比单独应用能更好地预测不良结局。CU比值预测新生儿不良结局的敏感性、特异性、阳性预测值和阴性预测值分别为61.3%、70.3%、56%和78.9%，而CP比值分别为42%、57.5%、62%和76%。结论。脑-子宫比值和脑-胎盘比值在预测围产期不良结局方面相互补充。单独来看，这两个比值对良好的围产期结局具有较高的阴性预测价值，令人安心。
