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外周神经的遗传性和获得性多神经病:临床考量与磁共振神经成像

Hereditary and acquired polyneuropathy conditions of the peripheral nerves: clinical considerations and MR neurography imaging.

作者信息

Trivedi Jaya R, Phillips Lauren, Chhabra Avneesh

机构信息

Department of Neurology and Neurotherapeutics, UT Southwestern Medical Center, Dallas, Texas.

Department of Radiology, UT Southwestern Medical Center, Dallas, Texas.

出版信息

Semin Musculoskelet Radiol. 2015 Apr;19(2):130-6. doi: 10.1055/s-0035-1545076. Epub 2015 Mar 12.

DOI:10.1055/s-0035-1545076
PMID:25764237
Abstract

Polyneuropathies can be classified as either primarily demyelinating or axonal, and further as hereditary or acquired. It is important to recognize acquired neuropathies because some are amenable to treatment. Clinical findings and electrophysiology are used in the routine diagnosis of these conditions. Magnetic resonance neurography (MRN) is a helpful supplementary diagnostic tool. This article discusses the typical clinical findings, electrophysiology findings, and MRN appearances of common hereditary or acquired neuropathies such as chronic inflammatory demyelinating neuropathy, multifocal motor neuropathy, diabetic neuropathy, chemotherapy-induced neuropathy, and postsurgical neuropathy.

摘要

多发性神经病可分为原发性脱髓鞘性或轴索性,还可进一步分为遗传性或获得性。认识到获得性神经病很重要,因为有些是可以治疗的。临床发现和电生理检查用于这些疾病的常规诊断。磁共振神经成像(MRN)是一种有用的辅助诊断工具。本文讨论了常见遗传性或获得性神经病(如慢性炎症性脱髓鞘性神经病、多灶性运动神经病、糖尿病性神经病、化疗引起的神经病和术后神经病)的典型临床发现、电生理检查结果及MRN表现。

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引用本文的文献

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Magnetic Resonance Imaging as a Biomarker in Rodent Peripheral Nerve Injury Models Reveals an Age-Related Impairment of Nerve Regeneration.磁共振成像作为啮齿动物周围神经损伤模型中的生物标志物,揭示了年龄相关的神经再生损伤。
Sci Rep. 2019 Sep 18;9(1):13508. doi: 10.1038/s41598-019-49850-2.
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Comparing of Cox model and parametric models in analysis of effective factors on event time of neuropathy in patients with type 2 diabetes.
2型糖尿病患者神经病变事件时间影响因素分析中Cox模型与参数模型的比较
J Res Med Sci. 2017 Oct 31;22:115. doi: 10.4103/jrms.JRMS_6_17. eCollection 2017.
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Magnetic resonance neurography: current perspectives and literature review.磁共振神经成像:当前的观点和文献综述。
Eur Radiol. 2018 Feb;28(2):698-707. doi: 10.1007/s00330-017-4976-8. Epub 2017 Jul 14.