†Department of Chemistry, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, United States.
‡Department of Materials Science and Engineering, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, United States.
ACS Appl Mater Interfaces. 2015 Apr 1;7(12):6359-68. doi: 10.1021/acsami.5b00484. Epub 2015 Mar 23.
Encapsulation of actives comprises an area of exploration undergoing rapid growth in both academic and industrial research settings. Encapsulation processes are employed as a part of product synthesis processes for improved efficiency, enhanced stability, active ingredient compatibility, increased safety, targeted delivery, and novel performance of the end product. Such technical benefits enable producers to offer products with increased formulation complexity, access new markets, differentiate products, and improve compatibility and stability, while meeting consumer demands with improved performance, reduced costs, and new actives. In this review, we highlight several emerging academic areas of encapsulation that we believe have specific relevance to industrial formulation, with a focus on three primary areas: supramolecular encapsulation, aqueous self-assembled systems, and emulsion-based capsules. The goal of this review is to help identify the major challenges facing encapsulation technology adoption in the chemical industry, bringing focus and maximizing the potential value of ongoing research efforts.
活性物质包封包含一个快速发展的领域,无论是在学术研究还是工业研究环境中。包封工艺被用作产品合成过程的一部分,以提高效率、增强稳定性、提高活性成分的相容性、增加安全性、靶向递送以及最终产品的新颖性能。这些技术优势使生产商能够提供具有更高配方复杂性的产品,进入新的市场,使产品差异化,并提高相容性和稳定性,同时满足消费者对性能提高、成本降低和新活性物质的需求。在这篇综述中,我们重点介绍了几个我们认为与工业配方具有特殊相关性的新兴学术领域的包封,主要关注三个领域:超分子包封、水相自组装体系和乳液基胶囊。本文的目的是帮助确定化学工业中采用包封技术面临的主要挑战,聚焦并最大化正在进行的研究工作的潜在价值。