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低强度激光与单独使用或联合使用精氨酸碳酸钙治疗牙本质过敏症的比较:一项随机分口临床研究。

Comparison of low level laser and arginine-calcium carbonate alone or combination in the treatment of dentin hypersensitivity: a randomized split-mouth clinical study.

作者信息

Bal Mehmet Vehbi, Keskiner İlker, Sezer Ufuk, Açıkel Cengizhan, Saygun Işıl

机构信息

1 Department of Periodontology, Dental Sciences Center, Gulhane Military Medical Academy , Ankara, Turkey .

出版信息

Photomed Laser Surg. 2015 Apr;33(4):200-5. doi: 10.1089/pho.2014.3873. Epub 2015 Mar 12.

Abstract

OBJECTIVE

This study aimed to compare the efficacy of low-level laser (LLL) and desensitizing paste (DP) containing 8% arginine-calcium carbonate, in the treatment of dentin hypersensitivity (DH) and also to determine whether their combined application would improve the efficacy of the treatment.

BACKGROUND DATA

There are various options for the treatment of DH; however, superiority of one method over others alone has not been currently demonstrated.

MATERIALS AND METHODS

Twenty-one patients with 156 teeth affected by DH were included in the study. Selected teeth were randomly divided into five groups: LLL, DP, laser followed by DP (LLL+DP), DP followed by laser (DP+LLL) applied to one of the quadrants, and a control group, consisting of a randomly selected additional tooth in one of the quadrants. Teeth were irradiated by the 685 nm diode laser treatment with 25 mW at 9 Hz for 100sec at 1 cm(2) area (2J/cm(2)) in interrupted mode. Pain response to evaporative stimulus was quantified on a visual analogue scale (VAS) over a 90-day period.

RESULTS

All four treatment groups experienced significant and persistent decrease in the mean VAS score immediately post-treatment until the end of the study, whereas the placebo group had high VAS scores throughout the study. On day 90, percent reduction in VAS scores was 72% for LLL, 65.4% for DP, 54.6% for LLL+DP, and 69.6% for DP+LLL, whereas the placebo group showed an increase of 7.8%.

CONCLUSIONS

The application of either LLL or DP containing 8% arginine-calcium carbonate appears to be effective in decreasing DH. However, their combined use does not improve the efficacy beyond what is attainable with either treatment alone.

摘要

目的

本研究旨在比较低强度激光(LLL)与含8%精氨酸 - 碳酸钙的脱敏糊剂(DP)治疗牙本质过敏症(DH)的疗效,并确定它们的联合应用是否会提高治疗效果。

背景数据

治疗DH有多种选择;然而,目前尚未证明一种方法相对于其他方法的优越性。

材料与方法

本研究纳入了21例患有156颗DH患牙的患者。将选定的牙齿随机分为五组:LLL组、DP组、先激光后DP组(LLL + DP)、先DP后激光组(DP + LLL),分别应用于一个象限,以及一个对照组,由在一个象限中随机选择的另一颗牙齿组成。用685nm二极管激光以25mW、9Hz的频率在1cm²区域(2J/cm²)以间断模式照射牙齿100秒。在90天内通过视觉模拟量表(VAS)对蒸发刺激的疼痛反应进行量化。

结果

在治疗后直至研究结束,所有四个治疗组的平均VAS评分均出现显著且持续的下降,而安慰剂组在整个研究过程中VAS评分较高。在第90天,LLL组VAS评分降低百分比为72%,DP组为65.4%,LLL + DP组为54.6%,DP + LLL组为69.6%,而安慰剂组增加了7.8%。

结论

应用LLL或含8%精氨酸 - 碳酸钙的DP似乎对降低DH有效。然而,它们的联合使用并没有比单独使用任何一种治疗方法更能提高疗效。

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Laser therapy for dentinal hypersensitivity.激光治疗牙本质过敏症。
Cochrane Database Syst Rev. 2021 Jul 13;7(7):CD009434. doi: 10.1002/14651858.CD009434.pub2.

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