Srimahachota Suphot, Sansanayudh Nakarin, Lertsuwunseri Vorarit, Cholteesupachai Jiranut, Lertsapcharoen Pornthep
J Med Assoc Thai. 2015 Jan;98 Suppl 1:S107-10.
The Cocoon PFO Occluder is a device for percutaneous closure of inter-atrial communications. Its self-centering characteristics make it attractive for closure of patent foramen ovales (PFOs) with or without atrial septal aneurysms. The goal of this study is to report the immediate and follow-up results of the first 14 patients in implanted with the Cocoon PFO Occluder.
This is a retrospective report of immediate and short-term clinical and echocardiographic outcome of patients who underwent transcatheter closure of PFO because of paradoxical embolism. Procedural success was defined as successful deployment of the device and effective occlusion (no, or trivial, shunt after device placement). All patients had a transesophageal echocardiography (TEE) with saline contrast injection at baseline and clinical follow-up at 6 months.
Between September 2012 and March 2014, 14 patients had successfully undergone transcatheter closure of PFO using Cocoon device. During follow-up none of the patients had a recurrence of stroke after device closure. No residual shunt was observed in any patients at follow-up.
Transcatheter closure of PFO with the Cocoon PFO device is safe and effective and can be used for preventing recurrent strokes in patients who present with cryptogenic stroke and PFO.
Cocoon卵圆孔未闭封堵器是一种用于经皮闭合房间隔交通的装置。其自定心特性使其对于闭合有无房间隔瘤的卵圆孔未闭（PFO）具有吸引力。本研究的目的是报告首批14例植入Cocoon卵圆孔未闭封堵器患者的即刻及随访结果。
这是一份关于因反常栓塞行经导管闭合PFO患者的即刻及短期临床和超声心动图结果的回顾性报告。手术成功定义为装置成功植入且封堵有效（装置置入后无分流或仅有微量分流）。所有患者在基线时接受经食管超声心动图（TEE）检查并注射生理盐水造影剂，在6个月时进行临床随访。
在2012年9月至2014年3月期间，14例患者成功使用Cocoon装置行经导管闭合PFO。在随访期间，所有患者在装置闭合后均未发生中风复发。随访时未观察到任何患者有残余分流。
使用Cocoon卵圆孔未闭装置行经导管闭合PFO安全有效，可用于预防隐源性中风合并PFO患者的中风复发。
