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肾静脉血栓形成的产前诊断:一例报告及文献综述

Prenatal Diagnosis of Renal Vein Thrombosis: A Case Report and Literature Review.

作者信息

Moaddab Amirhossein, Shamshirsaz Alireza A, Ruano Rodrigo, Salmanian Bahram, Lee Wesley, Belfort Michael A, Espinoza Jimmy

机构信息

Department of Obstetrics and Gynecology, Baylor College of Medicine and Texas Children's Fetal Center, Texas Children's Hospital Pavilion for Women, Houston, Tex., USA.

出版信息

Fetal Diagn Ther. 2016;39(3):228-33. doi: 10.1159/000375372. Epub 2015 Mar 10.

Abstract

BACKGROUND

Renal vein thrombosis (RVT) is a well-characterized condition among neonates; however, this complication is rarely diagnosed prenatally.

METHODS

In this report, we describe a fetus with unilateral RVT and summarize the literature regarding prenatal diagnostic criteria and postnatal prognosis. We searched the English, French and Spanish literature (MEDLINE, PubMed and EMBASE) for cases with prenatal diagnosis of RVT.

RESULTS

Including our case, a total of 23 fetuses with fetal RVT were reviewed in the present study. All cases were diagnosed in the third trimester, and the survival rate among these cases was 63%. Enlargement of the kidney was the most commonly associated initial ultrasound finding. The only ultrasound finding significantly associated with mortality was the presence of bilateral RVT.

DISCUSSION

The etiology of fetal RVT is still unclear. Considering the large number of cases with RVT that manifest in the first days of life, prenatal diagnosis of this condition has relevance.

摘要

背景

肾静脉血栓形成(RVT)在新生儿中是一种特征明确的病症;然而,这种并发症在产前很少被诊断出来。

方法

在本报告中,我们描述了一名患有单侧RVT的胎儿,并总结了有关产前诊断标准和产后预后的文献。我们在英文、法文和西班牙文文献(MEDLINE、PubMed和EMBASE)中搜索了产前诊断为RVT的病例。

结果

包括我们的病例在内,本研究共回顾了23例胎儿RVT病例。所有病例均在孕晚期被诊断出来,这些病例的存活率为63%。肾脏增大是最常见的相关初始超声检查结果。与死亡率显著相关的唯一超声检查结果是双侧RVT的存在。

讨论

胎儿RVT的病因仍不清楚。鉴于大量RVT病例在出生后的头几天出现,对这种病症进行产前诊断具有重要意义。

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