Hashemian Somayh, Ashrafzadeh Farah, Akhondian Javad, Beiraghi Toosi Mehran
1. Pediatric Neurology Department, Ghaem hospital, Mashhad University of Medical Sciences, Mashhad, Iran.
Iran J Child Neurol. 2015 Winter;9(1):107-10.
Many neurologic manifestations of Epstein-Barr virus (EBV) infection have been documented, including encephalitis, aseptic meningitis, transverse myelitis, and Guillain-Barre syndrome. These manifestations can occur alone or coincidentally with the clinical picture of infectious mononucleosis. EBV encephalitis is rare and is indicated as a wide range of clinical manifestations. We report a 10-year-old girl presented with fever, gait disturbance, and bizarre behavior for one week. The results of the physical examination were unremarkable. The diagnosis of EBV encephalitis was made by changes in titers of EBV specific antibodies and MRI findings. A cranial MRI demonstrated abnormal high signal intensities in the basal ganglia and the striatal body, especially in the putamen and caudate nucleus. EBV infection should be considered when lesions are localized to the basal ganglia.
已有文献记载了爱泼斯坦-巴尔病毒(EBV)感染的许多神经学表现,包括脑炎、无菌性脑膜炎、横贯性脊髓炎和格林-巴利综合征。这些表现可单独出现,或与传染性单核细胞增多症的临床表现同时出现。EBV脑炎罕见,表现为广泛的临床表现。我们报告一名10岁女孩,出现发热、步态障碍和怪异行为一周。体格检查结果无异常。通过EBV特异性抗体滴度变化和MRI检查结果确诊为EBV脑炎。头颅MRI显示基底神经节和纹状体异常高信号,尤其是壳核和尾状核。当病变局限于基底神经节时,应考虑EBV感染。