Onabolu Olanrewaju, Donos Nikos, Tu Yu-Kang, Darbar Ulpee, Nibali Luigi
Periodontology Unit and Division of Clinical Research, Eastman Dental Institute and Hospital, University College London (UCL), United Kingdom.
Graduate Institute of Epidemiology and Preventive Medicine, College of Public Health, National Taiwan University, Taipei, Taiwan.
J Dent. 2015 Jun;43(6):673-82. doi: 10.1016/j.jdent.2015.02.005. Epub 2015 Mar 10.
The current classification assumes that aggressive periodontitis (AgP) has a faster rate of progression than chronic periodontitis (CP). However, this has not been clearly proven and difficulties exist in establishing progression. This study aimed to assess the feasibility of retrospectively utilising previous records for clinical diagnosis of periodontal diseases and to assess if two different patterns of disease progression exist between AgP and CP.
Previous radiographic records of a cohort of 235 patients clinically diagnosed with AgP or CP were requested from the referring general dental practitioners (GDPs). Comparable radiographic records were analysed in order to assess progression patterns and associate these with clinical diagnosis, by multilevel analysis.
43 patients out of the initial 235 had comparable radiographs retrieved from the GDPs. 858 sites were followed for an average 6.6 years. Radiographically, AgP showed a faster linear pattern of progression than CP (0.31mm/year vs. 0.20mm/year, p<0.001).
This study provides evidence for a faster disease progression in untreated AgP compared to CP as assessed by radiographic bone levels. Furthermore, it shows that retrievability of previous radiographs from GDPs is unpredictable and GDPs should be encouraged to send them along with their referral.
The importance of differentially diagnosing AgP and CP might be useful in establishing a clinically relevant definition for periodontal disease progression and may have an impact on the clinical management of aggressive periodontitis, since our findings show that there is continuous destruction in patients with aggressive periodontitis if left untreated.
目前的分类认为侵袭性牙周炎(AgP)的进展速度比慢性牙周炎(CP)快。然而,这一点尚未得到明确证实,且在确定疾病进展方面存在困难。本研究旨在评估回顾性利用既往记录进行牙周疾病临床诊断的可行性,并评估AgP和CP之间是否存在两种不同的疾病进展模式。
向转诊的普通牙科医生(GDPs)索取了一组235例临床诊断为AgP或CP患者的既往影像学记录。通过多水平分析对可比的影像学记录进行分析,以评估进展模式并将其与临床诊断相关联。
最初的235例患者中有43例从GDPs处获取了可比的X线片。对858个位点进行了平均6.6年的随访。影像学上,AgP的线性进展模式比CP更快(0.31mm/年对0.20mm/年,p<0.001)。
本研究提供了证据,表明通过影像学骨水平评估,未经治疗的AgP比CP疾病进展更快。此外,研究表明从GDPs处获取既往X线片的可检索性不可预测,应鼓励GDPs在转诊时一并发送这些片子。
鉴别诊断AgP和CP的重要性可能有助于建立牙周疾病进展的临床相关定义,并且可能对侵袭性牙周炎的临床管理产生影响,因为我们的研究结果表明,如果不进行治疗,侵袭性牙周炎患者会持续出现组织破坏。