Chen Yabin, Shi Wei, Hui Yonghai, Sun Xinhua, Xu Linxian, Feng Lei, Xie Zhengfeng
Key Laboratory of Oil & Gas Fine Chemicals, Ministry of Education, College of Chemistry and Chemical Engineering, Xinjiang University, Urumqi 830046, Xinjiang, PR China.
Key Laboratory of Oil & Gas Fine Chemicals, Ministry of Education, College of Chemistry and Chemical Engineering, Xinjiang University, Urumqi 830046, Xinjiang, PR China.
Talanta. 2015 May;137:38-42. doi: 10.1016/j.talanta.2015.01.018. Epub 2015 Jan 19.
A new simple molecule, 2-((2-phenyl-2H-1,2,3-triazol-4-yl)methylene)malononitrile (M1), was synthesized successfully by the Knoevenagel condensation reaction between 2-phenyl-1,2,3-triazole-4-carboxaldehyde and malononitrile. The receptor M1 is highly sensitive and selective to cyanide anion due to the nucleophilic addition of cyanide anion with M1. Distinct changes on UV-vis and fluorescence spectra can be detected with the addition of cyanide anion to the DMSO solution of M1. Optical properties of M1 were scarcely affected by the addition of other common background anions (F(-), Cl(-), Br(-), I(-), SCN(-), OH(-), CO4(2-), H2PO4(-), SO4(2-), HSO4(-), AcO(-), and NO3(-)) under the same condition. The detection limit of CN(-) reaches ~1.43 μM by M1 and the presence of background anions brought very slight interference for the detection of CN(-).
通过2-苯基-1,2,3-三唑-4-甲醛与丙二腈之间的Knoevenagel缩合反应，成功合成了一种新型简单分子2-((2-苯基-2H-1,2,3-三唑-4-基)亚甲基)丙二腈(M1)。受体M1对氰根阴离子具有高度敏感性和选择性，这是由于氰根阴离子与M1发生亲核加成反应。向M1的二甲基亚砜溶液中加入氰根阴离子时，可检测到紫外可见光谱和荧光光谱发生明显变化。在相同条件下，加入其他常见背景阴离子(F(-)、Cl(-)、Br(-)、I(-)、SCN(-)、OH(-)、CO4(2-)、H2PO4(-)、SO4(2-)、HSO4(-)、AcO(-)和NO3(-))对M1的光学性质几乎没有影响。M1对CN(-)的检测限达到~1.43 μM，背景阴离子的存在对CN(-)的检测产生的干扰非常小。
