Adler C P
Pathologisches Institut, Universität Freiburg.
Langenbecks Arch Chir Suppl II Verh Dtsch Ges Chir. 1989:479-86.
A bone fracture is a complete or incomplete discontinuity of bone caused by a direct or indirect force. A pathological bone fracture is a bone fracture which occurs without adequate trauma and is caused by a preexistent pathological bone lesion. Causes include resorption of bone mass (osteoporosis), reduction of bone quality (osteomalacia, osteonecrosis), insufficient bone production (osteogenesis imperfecta, fibrous dysplasia), augmented bone resorption (giant cell granulomas, aneurysmal bone cyst), pathological bone remodelling (Paget's disease), or local bone destruction due to tumorous growths. A pathological bone fracture has to be detected clinically as well as radiologically and its cause diagnosed histologically in order to ensure adequate therapy.
骨折是指由直接或间接外力导致的骨的完全或不完全连续性中断。病理性骨折是指在没有足够外伤的情况下发生的骨折,由先前存在的病理性骨病变引起。病因包括骨质吸收(骨质疏松症)、骨质质量下降(骨软化症、骨坏死)、骨生成不足(成骨不全、骨纤维异常增殖症)、骨质吸收增加(巨细胞肉芽肿、动脉瘤样骨囊肿)、病理性骨重塑(佩吉特病)或肿瘤生长导致的局部骨质破坏。病理性骨折必须通过临床及影像学检查来发现,并通过组织学诊断其病因,以确保进行适当的治疗。