Suppr超能文献

激光微槽、精氨酸-甘氨酸-天冬氨酸(RGD)涂层牙种植体:5年影像学随访

Laser micro-grooved, Arginine-Glycine-Apspartic acid (RGD) coated dental implants, a 5 years radiographic follow-up.

作者信息

Alkhodary Mohamed Ahmed

机构信息

Lecturer of Removable Prosthodontics, Faculty of Dentistry, Alexandria University, Egypt, Assistant Professor of Prosthetic Dental Science, College of Dentistry, Al Qassim University, KSA.

出版信息

Int J Health Sci (Qassim). 2014 Oct;8(4):361-9.

Abstract

OBJECTIVES

This work has utilized laser direct writing to produce 10 microns wide uniform grooves on the surface of custom made titanium (Ti-6Al-4V) dental implants, and the tri-peptide RGD coating to produce a micromechanical and a chemical union with the tissues around the implant crest module and minimize crestal bone loss. The aim of this study was to follow these implants radiographically after five years of service under a mandibular overdenture.

METHODOLOGY

Standardized digital periapical radiographs and the computer software "Image J" were used to evaluate the bone density profile and vertical bone loss along the mesial and distal sides of the implants used in this study.

RESULTS

The results of this study demonstrated less vertical bone loss and higher bone density profiles next to the laser microgrooved implants coated with the RGD than those only having the laser micro-grooves.

CONCLUSION

The RGD coating has improved the bone density profile and reduced the vertical bone loss around the studied dental implants. However, further studies are needed to compare the effects of the laser micro-grooves versus other uniform or non uniform surface features; also, the RGD coating should be compared to other biomimetic surface coating materials.

摘要

目的

本研究利用激光直写技术在定制的钛(Ti-6Al-4V)牙种植体表面制作出宽度为10微米的均匀凹槽,并采用三肽RGD涂层,以与种植体颈部模块周围的组织形成微机械和化学结合,减少牙槽嵴骨吸收。本研究的目的是在下颌覆盖义齿下使用五年后,通过影像学方法追踪这些种植体。

方法

使用标准化的数字化根尖片和计算机软件“Image J”来评估本研究中使用的种植体近中和远中侧的骨密度分布和垂直骨吸收情况。

结果

本研究结果表明,与仅具有激光微槽的种植体相比,涂有RGD的激光微槽种植体旁的垂直骨吸收更少,骨密度更高。

结论

RGD涂层改善了所研究牙种植体周围的骨密度分布,减少了垂直骨吸收。然而,需要进一步研究来比较激光微槽与其他均匀或不均匀表面特征的效果;此外,应将RGD涂层与其他仿生表面涂层材料进行比较。

相似文献

本文引用的文献

6
Proteins and their peptide motifs in acellular apatite mineralization of scaffolds for tissue engineering.
Tissue Eng Part B Rev. 2008 Dec;14(4):433-45. doi: 10.1089/ten.teb.2008.0121.
8
Implants and/or teeth: consensus statements and recommendations.
J Oral Rehabil. 2008 Jan;35 Suppl 1:2-8. doi: 10.1111/j.1365-2842.2007.01833.x.
9
Cell/surface interactions and adhesion on Ti-6Al-4V: effects of surface texture.
J Biomed Mater Res B Appl Biomater. 2007 Aug;82(2):360-73. doi: 10.1002/jbm.b.30741.

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验