Alkhodary Mohamed Ahmed
Lecturer of Removable Prosthodontics, Faculty of Dentistry, Alexandria University, Egypt, Assistant Professor of Prosthetic Dental Science, College of Dentistry, Al Qassim University, KSA.
Int J Health Sci (Qassim). 2014 Oct;8(4):361-9.
This work has utilized laser direct writing to produce 10 microns wide uniform grooves on the surface of custom made titanium (Ti-6Al-4V) dental implants, and the tri-peptide RGD coating to produce a micromechanical and a chemical union with the tissues around the implant crest module and minimize crestal bone loss. The aim of this study was to follow these implants radiographically after five years of service under a mandibular overdenture.
Standardized digital periapical radiographs and the computer software "Image J" were used to evaluate the bone density profile and vertical bone loss along the mesial and distal sides of the implants used in this study.
The results of this study demonstrated less vertical bone loss and higher bone density profiles next to the laser microgrooved implants coated with the RGD than those only having the laser micro-grooves.
The RGD coating has improved the bone density profile and reduced the vertical bone loss around the studied dental implants. However, further studies are needed to compare the effects of the laser micro-grooves versus other uniform or non uniform surface features; also, the RGD coating should be compared to other biomimetic surface coating materials.
本研究利用激光直写技术在定制的钛(Ti-6Al-4V)牙种植体表面制作出宽度为10微米的均匀凹槽,并采用三肽RGD涂层,以与种植体颈部模块周围的组织形成微机械和化学结合,减少牙槽嵴骨吸收。本研究的目的是在下颌覆盖义齿下使用五年后,通过影像学方法追踪这些种植体。
使用标准化的数字化根尖片和计算机软件“Image J”来评估本研究中使用的种植体近中和远中侧的骨密度分布和垂直骨吸收情况。
本研究结果表明,与仅具有激光微槽的种植体相比,涂有RGD的激光微槽种植体旁的垂直骨吸收更少,骨密度更高。
RGD涂层改善了所研究牙种植体周围的骨密度分布,减少了垂直骨吸收。然而,需要进一步研究来比较激光微槽与其他均匀或不均匀表面特征的效果;此外,应将RGD涂层与其他仿生表面涂层材料进行比较。