Almagro U A
Cancer. 1985 Feb 1;55(3):608-14. doi: 10.1002/1097-0142(19850201)55:3<608::aid-cncr2820550322>3.0.co;2-s.
An unusual prostatic neoplasm characterized by a carcinoid-like light microscopic pattern together with argyrophilia of tumor cells is described. Immunoperoxidase stain for prostatic specific antigen, however, was positive, indicating that this neoplasm was an argyrophilic prostatic carcinoma. Although the clinical significance of a carcinoid-like pattern and/or argyrophilia in prostatic carcinoma is currently unknown, pathologic recognition of these features is of paramount importance because prostatic carcinoma with these features has to be distinguished from true primary prostatic carcinoid tumor or, in areas of metastasis, from metastatic carcinoid originating from other sites such as the gastrointestinal or respiratory tracts. The value of the immunoperoxidase technique for prostatic specific antigen as well as prostatic acid phosphatase in this differentiation is stressed.
本文描述了一种不寻常的前列腺肿瘤，其特征为类癌样的光镜下形态以及肿瘤细胞的嗜银性。然而，前列腺特异性抗原的免疫过氧化物酶染色呈阳性，表明该肿瘤为嗜银性前列腺癌。尽管目前前列腺癌中类癌样形态和/或嗜银性的临床意义尚不清楚，但对这些特征的病理识别至关重要，因为具有这些特征的前列腺癌必须与真正的原发性前列腺类癌肿瘤相区分，或者在转移部位与源自其他部位（如胃肠道或呼吸道）的转移性类癌相区分。强调了免疫过氧化物酶技术检测前列腺特异性抗原以及前列腺酸性磷酸酶在这种鉴别诊断中的价值。
