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粪便转流能否预防克罗恩病回盲部切除术后的发病情况?80例回顾性系列研究。

Does faecal diversion prevent morbidity after ileocecal resection for Crohn's disease? Retrospective series of 80 cases.

作者信息

Mege Diane, Bege Thierry, Beyer-Berjot Laura, Loundou Anderson, Grimaud Jean-Charles, Brunet Christian, Berdah Stéphane

机构信息

Department of Digestive Surgery, Hôpital Nord, Assistance Publique-Hôpitaux de Marseille, Université de la Méditerranée, Marseille, France.

Laboratory of Biomechanics and Applications UMRT24, Marseille, France.

出版信息

ANZ J Surg. 2017 Sep;87(9):E74-E79. doi: 10.1111/ans.13034. Epub 2015 Mar 17.

DOI:10.1111/ans.13034
PMID:25780907
Abstract

BACKGROUND

After ileocecal resection for Crohn's disease, a temporary faecal diversion is indicated in high-risk patients. The impact of a temporary stoma on post-operative morbidity has been poorly assessed so far. The aim was to analyse post-operative morbidity of temporary faecal diversion after ileocecal resection for Crohn's disease.

METHODS

Patients undergoing temporary faecal diversion combined with ileocecal resection were retrospectively included. Patients presenting with complications were compared with patients with an uneventful post-operative course, to identify any predictive factor for morbidity.

RESULTS

Eighty faecal diversions were performed (43 males, 33.5 (18-75) years), including 63 split stoma (79%) and 17 covering loop ileostomies (21%). Fifty-two patients (65%) presented with a perforating disease. Post-operative complications occurred in 15 patients (19%), 15 days after surgery (1-30). The main complications were intra-abdominal abscess (n = 6), functional renal failure (n = 6), fistula (n = 2) and stomal prolapse (n = 2). Two patients required surgery. Previous bowel resections (60% versus 28%, P = 0.01) were significantly associated with post-operative morbidity.

CONCLUSIONS

Temporary faecal diversion is useful in high-risk patients after ileocecal resection for Crohn's disease. Patients' information about post-operative risks remains an important issue. Risk factors for post-operative morbidity despite faecal diversion are previous bowel resections.

摘要

背景

对于克罗恩病患者行回盲部切除术后,高危患者需行临时性粪便转流。目前,临时性造口对术后发病率的影响评估不足。本研究旨在分析克罗恩病患者回盲部切除术后临时性粪便转流的术后发病率。

方法

回顾性纳入行临时性粪便转流联合回盲部切除术的患者。将出现并发症的患者与术后过程顺利的患者进行比较,以确定任何发病率的预测因素。

结果

共进行了80次粪便转流手术(43例男性,年龄33.5岁(18 - 75岁)),其中包括63例分流造口(79%)和17例覆盖式袢状回肠造口(21%)。52例患者(65%)患有穿孔性疾病。15例患者(19%)术后出现并发症,发生在术后15天(1 - 30天)。主要并发症为腹腔内脓肿(n = 6)、功能性肾衰竭(n = 6)、瘘管(n = 2)和造口脱垂(n = 2)。2例患者需要再次手术。既往肠道切除术(60% 对 28%,P = 0.01)与术后发病率显著相关。

结论

对于克罗恩病患者回盲部切除术后的高危患者,临时性粪便转流是有用的。告知患者术后风险仍然是一个重要问题。尽管进行了粪便转流,术后发病的危险因素是既往肠道切除术。

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