父母隐匿性乳糜泻对新生儿出生体重和胎龄影响的评估
The Evaluation of The Effects of Paternal And Maternal Silent Coeliac Disease on Birthweight and Gestational Age in Newborns.
作者信息
Kahveci H, Turan M I, Cayir A, Laloglu F, Ertekin V, Orbak Z
机构信息
Ministry of Health Education and Research Hospital, Erzurum, Turkey.
Regional Training and Research Hospital, Department of Pediatric Neurology, Diyarbakir, Turkey,
出版信息
West Indian Med J. 2014 Sep;63(5):470-3. doi: 10.7727/wimj.2013.166. Epub 2014 Jun 10.
OBJECTIVE
Coeliac disease is a chronic disease and is common all over the world. It has many other associated systemic side effects. This study investigated the effect of paternal and maternal silent coeliac disease on birthweight and gestational age in newborns.
METHODS
The study group consisted of 81 newborns who were hospitalized for prematurity or term-intrauterine growth retardation. The parents of premature and/or small for gestational age babies born with coeliac disease-specific antigens were investigated.
RESULTS
The differences were not statistically significant in fathers' tissue transglutaminase levels between premature appropriate gestational age, premature small gestational age and term small gestational age infants (p > 0.05), but statistically significant in mothers (p < 0.05).
CONCLUSIONS
Silent coeliac disease may occur in parents, especially in mothers of preterm and small for gestational age infants, even in the absence of apparent clinical indications.
目的
乳糜泻是一种慢性疾病，在全球范围内都很常见。它还有许多其他相关的全身性副作用。本研究调查了父母隐性乳糜泻对新生儿出生体重和胎龄的影响。
方法
研究组由81名因早产或足月宫内生长迟缓而住院的新生儿组成。对患有乳糜泻特异性抗原的早产和/或小于胎龄儿的父母进行了调查。
结果
早产适于胎龄儿、早产小于胎龄儿和足月小于胎龄儿父亲的组织转谷氨酰胺酶水平差异无统计学意义（p>0.05），但母亲的差异有统计学意义（p<0.05）。
结论
隐性乳糜泻可能发生在父母身上，尤其是早产和小于胎龄儿的母亲，即使没有明显的临床指征。
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