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钝性腹部实性器官损伤非手术治疗患者创伤后假性动脉瘤的研究。

The investigation of posttraumatic pseudoaneurysms in patients treated with nonoperative management for blunt abdominal solid organ injuries.

作者信息

Kittaka Hirotada, Yagi Yoshiki, Zushi Ryosuke, Hazui Hiroshi, Akimoto Hiroshi

机构信息

Department of Emergency, Osaka Misihima Emergency Critical Care Center, 11-1, Minami-Akutagawa-cho, Takatsuki City, Osaka Prefecture, Japan.

出版信息

PLoS One. 2015 Mar 17;10(3):e0121078. doi: 10.1371/journal.pone.0121078. eCollection 2015.

Abstract

BACKGROUND

Posttraumatic pseudoaneurysms (PAs) have been recognized as the cause of delayed hemorrhage complicated with nonoperative management (NOM), although the need for intervention in patients with small-sized PAs and the relationship between the occurrence of PAs and bed-rest has been also unclear.

OBJECTIVES

The purpose of this study was to investigate the clinical history of small-sized PAs (less than 10 mm in diameter) which occurred in abdominal solid organs, and to analyze the relationship between the occurrence of PAs and early mobilization from bed.

METHODS

Sixty-two patients who were successfully managed with NOM were investigated. Mobilization within three days post-injury was defined as "early mobilization" and bed-rest lasting over three days was defined as "late mobilization." A comparison of the clinical factors, including the duration of bed-rest between patients with and without PAs detected by follow-up CT was performed. Furthermore, a multiple logistic regression model analysis on the occurrence of PAs was performed.

RESULTS

PAs were detected in 7 of the 62 patients. The One patient with PAs measuring larger than 10 mm received trans-arterial embolization, and the remaining six patients with PAs smaller than 10 mm were managed conservatively. Consequently, no delayed hemorrhage occurred, and the PAs spontaneously disappeared in all of the six patients managed without intervention. The multiple regression model analysis revealed that early mobilization was not a significant factor predicting new-onset PAs.

CONCLUSIONS

Small PAs can be expected to disappear spontaneously. Moreover, early mobilization is not a significant risk factor for the occurrence of PAs.

摘要

背景

创伤后假性动脉瘤(PAs)已被确认为非手术治疗(NOM)后延迟出血的原因,尽管对于小型PAs患者是否需要干预以及PAs的发生与卧床休息之间的关系尚不清楚。

目的

本研究旨在调查腹部实性器官中出现的小型PAs(直径小于10mm)的临床病史,并分析PAs的发生与早期下床活动之间的关系。

方法

对62例成功接受NOM治疗的患者进行调查。受伤后三天内的活动定义为“早期活动”,持续超过三天的卧床休息定义为“晚期卧床休息”。对随访CT检测到有或无PAs的患者之间的临床因素进行比较,包括卧床休息时间。此外,对PAs的发生进行多因素逻辑回归模型分析。

结果

62例患者中有7例检测到PAs。1例PA直径大于10mm的患者接受了经动脉栓塞治疗,其余6例PA小于10mm的患者采用保守治疗。结果,未发生延迟出血,6例未经干预治疗的患者的PAs均自发消失。多因素回归模型分析显示,早期活动不是预测新发PAs的重要因素。

结论

小型PAs有望自发消失。此外,早期活动不是PAs发生的重要危险因素。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6691/4363468/8f5a9a7e7183/pone.0121078.g001.jpg

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