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保乳手术后立即进行自体脂肪移植重建。

Immediate Reconstruction with Autologous fat Transfer Following Breast-Conserving Surgery.

作者信息

Biazus Jorge Villanova, Falcão Christiane Cardoso, Parizotto Angela Ceconello, Stumpf Camile Cesa, Cavalheiro José Antônio Crespo, Schuh Fernando, Cericatto Rodrigo, Zucatto Ângela Erguy, Melo Márcia Portela

机构信息

Breast Unit of Hospital de Clínicas de Porto Alegre, Federal University of Rio Grande do Sul, Medical School, Porto Alegre, Brazil.

出版信息

Breast J. 2015 May-Jun;21(3):268-75. doi: 10.1111/tbj.12397. Epub 2015 Mar 17.

Abstract

This study explores the technical viability of autologous fat grafting for immediate partial breast reconstruction following the primary conservative surgery for breast cancer; restoring volume, shape, and symmetry to the treated breast. We analyze the impact in relation to mammographic follow-up and the subjective degree of satisfaction with esthetic results and although we didn't have any local failure during the observation period; we understand that is too early for any kind of conclusion. From June of 2010 to July of 2011, 20 patients were selected for breast-conserving surgery (BCS) with partial breast reconstruction with autologous fat grafting performed during the same operation by the same medical team. The fat graft was injected in the subcutaneous and intraglandular breast tissue around the resected area. We performed an overcorrection, predicting a resorbing of about 30-50% of the volume grafted. All patients received the literature-based recommendations for breast cancer treatment with complementary radiotherapy. The follow-up period after the completion of radiotherapy ranged from 13 to 29 months. The average volume grafted was 121 cc and it was 2.1 times larger than the resected volume. The esthetic scores were considered very good or good in the majority of cases. Mammograms were taken every 6 months after radiotherapy and only one patient had a mammogram classified as BI-RADS 3, suggesting fat necrosis. The remaining patients were classified as BI-RADS 2. Immediate autologous fat grafting is a promising technique for partial breast reconstruction after BCS. It is associated with high patient and physician satisfaction. It is an alternative for reconstruction of small- and medium-sized breasts. This technique has the advantage that enables the reconstruction of defects in areas difficult to repair, particularly in the upper inner quadrants. It also may reduce the need for major glandular or myocutaneous flaps mobilization.

摘要

本研究探讨了自体脂肪移植用于乳腺癌一期保乳手术后即刻部分乳房重建的技术可行性,旨在恢复治疗侧乳房的体积、形状和对称性。我们分析了其与乳房X线摄影随访以及美学效果主观满意度的关系,尽管在观察期内未出现任何局部失败情况,但我们明白现在得出任何结论都为时过早。2010年6月至2011年7月,选取20例患者接受保乳手术(BCS),并由同一医疗团队在同一手术中进行自体脂肪移植部分乳房重建。将脂肪移植注射到切除区域周围的皮下和腺内乳房组织中。我们进行了过度矫正,预计移植体积约有30% - 50%会被吸收。所有患者均接受了基于文献的乳腺癌治疗及辅助放疗建议。放疗结束后的随访期为13至29个月。平均移植体积为121立方厘米,是切除体积的2.1倍。在大多数情况下,美学评分被认为非常好或良好。放疗后每6个月进行乳房X线摄影,只有1例患者的乳房X线摄影结果被分类为BI - RADS 3,提示脂肪坏死。其余患者被分类为BI - RADS 2。即刻自体脂肪移植是BCS术后部分乳房重建的一项有前景的技术。它与患者和医生的高满意度相关。它是中小型乳房重建的一种选择。该技术的优点在于能够修复难以修复区域的缺损,尤其是上内象限。它还可能减少对大的腺体或肌皮瓣转移的需求。

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