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保乳手术后游离真皮脂肪移植乳房重建的手术及肿瘤学结果

Surgical and oncological outcomes of free dermal fat graft for breast reconstruction after breast-conserving surgery.

作者信息

Biasio Fabrizio De, Bertozzi Serena, Londero Ambrogio P, Almesberger Daria, Zanin Chiara, Marchesi Andrea, Cedolini Carla, Risaliti Andrea, Parodi Pier C

机构信息

Clinic of Plastic and Reconstructive Surgery, Department of Medical Area, University of Udine, Italy.

Clinic of Surgery, Department of Medical Area, University of Udine, Italy.

出版信息

Adv Clin Exp Med. 2018 Jun;27(6):773-780. doi: 10.17219/acem/68977.

DOI:10.17219/acem/68977
PMID:29790683
Abstract

BACKGROUND

Oncoplastic breast surgery originated in order to improve the esthetic result of breast-conserving surgery (BCS). Autologous free dermal fat graft (FDFG) is an emerging oncoplastic technique to improve the cosmetic outcome of breast-conserving surgery.

OBJECTIVES

The aim of this study was to analyze our experience with FDFGs in breast reconstruction after breast-conserving surgery. Oncological outcomes, surgical complications and cosmetic results were considered.

MATERIAL AND METHODS

This retrospective chart review study considered all consecutive oncoplastic breast treatment by means of FDFG reconstruction during the period between September 2011 and September 2012 in our Clinic of Surgery (University of Udine, Italy). The data collected included patient and tumor characteristics and outcomes (cosmetic and oncological).

RESULTS

During the study period, 37 women were treated by breast cancer surgery and immediate breast reconstruction by FDFG. At a 3-year follow-up, we found no cases of recurrence among breast cancer patients treated by FDFG; at a 18-month follow-up, we found a prevalence of 75.0% of women extremely satisfied with their oncoplastic surgery and a high prevalence of excellent or good cosmetic outcomes (70.3%) according to objective and subjective cosmetic assessment.

CONCLUSIONS

Immediate breast reconstruction by FDFG after BCS in a population selected for a low risk of breast cancer recurrence seems to be an oncologically safe option, with a good cosmetic outcome and a high prevalence of women satisfied with the treatment.

摘要

背景

肿瘤整形乳房手术起源于改善保乳手术(BCS)的美学效果。自体游离真皮脂肪移植(FDFG)是一种新兴的肿瘤整形技术,用于改善保乳手术的美容效果。

目的

本研究的目的是分析我们在保乳手术后使用FDFG进行乳房重建的经验。考虑了肿瘤学结果、手术并发症和美容效果。

材料与方法

这项回顾性图表审查研究纳入了2011年9月至2012年9月期间在我们外科诊所(意大利乌迪内大学)通过FDFG重建进行的所有连续性肿瘤整形乳房治疗。收集的数据包括患者和肿瘤特征及结果(美容和肿瘤学方面)。

结果

在研究期间,37名女性接受了乳腺癌手术并通过FDFG进行了即刻乳房重建。在3年随访时,我们发现接受FDFG治疗的乳腺癌患者中无复发病例;在18个月随访时,根据客观和主观美容评估,我们发现75.0%的女性对其肿瘤整形手术极为满意,优秀或良好美容效果的比例很高(70.3%)。

结论

在选择的乳腺癌复发风险较低的人群中,BCS后通过FDFG进行即刻乳房重建似乎是一种肿瘤学上安全的选择,具有良好的美容效果,且女性对治疗的满意度很高。

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Gland Surg. 2021 Oct;10(10):2885-2889. doi: 10.21037/gs-21-563.
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Lipofilling after breast conserving surgery: a comprehensive literature review investigating its oncologic safety.
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Gland Surg. 2019 Oct;8(5):569-580. doi: 10.21037/gs.2019.09.09.