使用即时检测仪器研究海拔高度对糖化血红蛋白测量的影响。
Study of the effect of altitude on the measurement of glycated haemoglobin using point-of-care instruments.
作者信息
Veigne Sandra W, Sobngwi Eugene, Nouthe Brice E, Sobngwi-Tambekou Joelle, Balti Eric V, Limen Serge, Dehayem Mesmin Y, Ama Vicky, Nguewa Jean- Louis, Ndour-Mbaye Maimouna, Camara Alioune, Balde Naby M, Mbanya Jean- Claude
机构信息
National Obesity Center, Yaoundé Central Hospital and Faculty of Medicine and Biomedical Sciences, University of Yaoundé 1, Yaoundé, Cameroon.
National Obesity Center, Yaoundé Central Hospital and Faculty of Medicine and Biomedical Sciences, University of Yaoundé 1, Yaoundé, Cameroon; Molecular Medicine and Metabolism Laboratories, Bio-technology Center, University of Yaoundé 1, Yaoundé, Cameroon.
出版信息
Cardiovasc J Afr. 2015 Jan-Feb;26(1):38-40. doi: 10.5830/CVJA-2014-078.
We measured the glycated haemoglobin (HbA1c) levels of a total of 24 non-diabetic volunteers and diabetic patients using a point-of-care (POC) analyser in three Cameroonian cities at different altitudes. Although 12 to 25% of duplicates had more than 0.5% (8 mmol/mol) difference across the sites, HbA1c values correlated significantly (r = 0.89-0.96). Further calibration studies against gold-standard measures are warranted.
我们使用即时检验（POC）分析仪，在喀麦隆三个不同海拔的城市，对总共24名非糖尿病志愿者和糖尿病患者的糖化血红蛋白（HbA1c）水平进行了测量。尽管在不同地点，12%至25%的重复测量结果相差超过0.5%（8 mmol/mol），但HbA1c值之间仍存在显著相关性（r = 0.89 - 0.96）。有必要针对金标准测量方法开展进一步的校准研究。
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